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Showing result 1 - 5 of 470 swedish dissertations matching the above criteria.
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1. Glycolytic oscillations in individual yeast cells
Abstract : Oscillations in the concentration of yeast glycolytic intermediates have been intensively studied since the 1950s, but these studies have so far been limited to observations of average oscillatory behavior in synchronized cultures. Hence, it has remained unknown whether the onset of oscillations is a collective property of the population which requires a high cell density, or if individual cells can oscillate also in isolation. READ MORE
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2. Tunable superconducting resonators, subharmonic oscillations and manipulation of microwaves
Abstract : In this thesis I present different types of manipulations of microwave fields using tunable superconducting resonators. A resonator is made tunable by adding one or more superconducting quantum interference devices, SQUIDs. The SQUID consists of a superconducting loop with two Josephson junctions and acts as a tunable nonlinear inductor. READ MORE
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3. The Art of Modelling Oscillations and Feedback across Biological Scales
Abstract : This thesis consists of four papers in the field of mathematical biology. All papers aim to advance our understanding of biological systems through the development and application of innovative mathematical models. READ MORE
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4. Single Cell Studies of Glycolytic Oscillations Using Microfluidics and Optical Tweezers
Abstract : The complex set of reactions in metabolism has been extensively studied in populations with millions of cells, but much information can still be gained by studying the heterogeneous metabolic behaviour in individual cells. The first part of energy metabolism is called glycolysis and is very similar in mammalian cells, such as human cells, and in yeast cells. READ MORE
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5. On the Generation of cAMP Oscillations and Regulation of the Ca2+ Store-operated Pathway in Pancreatic Islet α- and β-cells
Abstract : Insulin and glucagon are released in pulses from pancreatic β- and α-cells, respectively. Both cell types are electrically excitable, and elevation of the cytoplasmic Ca2+ concentration ([Ca2+]i) due to depolarization with voltage-dependent entry of the cation is the main trigger of hormone secretion. READ MORE