Search for dissertations about: "Oskar Skog"
Showing result 1 - 5 of 6 swedish dissertations containing the words Oskar Skog.
-
1. Effects of Enterovirus Infection on Innate Immunity and Beta Cell Function in Human Islets of Langerhans
Abstract : This thesis focuses on enteroviral effects on human pancreatic islets. Most knowledge of viral effects on host cells relies on studies of immortalized cell lines or animal models. The islets represent a fundamentally different and less well studied cellular host. Also, enterovirus has been implicated in the etiology of type 1 diabetes (T1D). READ MORE
-
2. Studies of the human pancreas to understand the pathologic events leading to type 1 diabetes
Abstract : Type 1 diabetes (T1D) is classically described as a disease emanating from beta-cell loss, and as such, the beta cells have been the main target of investigation. However, recent years have witnessed a shift in perspective, with T1D being increasingly recognized as a condition that affects the entire pancreas. READ MORE
-
3. Characterization of the Pancreas in Type 1 and Type 2 Diabetes
Abstract : Diabetes is recognized by hyperglycaemia and polyuria. Complications, reduced quality of life and staggering health-care costs are all derived from the disease. Two subclasses of diabetes are Type 1 diabetes (T1D) and Type 2 diabetes (T2D). READ MORE
-
4. Studies of the Pancreas: Implications for Type 1 Diabetes Aetiology
Abstract : Type 1 diabetes (T1D) is a disease of severe insulin deficiency through loss of β cells in the endocrine pancreas. The T1D dogma maintains that a precipitating event unleashes autoimmunity in at-risk individuals, often measured through autoantibodies against β cell antigens. READ MORE
-
5. Transcriptional and morphological analysis of organ donor pancreata
Abstract : The diabetes disease panorama affects more than 400 million people world wide – a number projected to rise above 640 million in the next 20 years. Type 1 and type 2 diabetes are associated with adverse complications, resulting in severe morbidity and high healthcare costs exerting substantial strain on society. READ MORE