Search for dissertations about: "Osteocalcin"

Showing result 11 - 15 of 31 swedish dissertations containing the word Osteocalcin.

2. 11. Polyester scaffold: Material design and cell-protein-material interaction

   Author : Staffan Dånmark; Anna Finne-Wistrand; Ann-Christine Albertsson; Kamal Mustafa; Pentti Tengvall; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Abstract : Tissue engineering has emerged as a valid approach for the regeneration and restoration of bone defects. The concept of bone tissue engineering includes degradable scaffolds, osteogenic cells and osteoinductive growth factors either alone or in any combination of these three. READ MORE

4. 12. Physiological and clinical studies of calcium-regulating hormones calcitonin and parathyroid hormone-related protein

   Author : Haiqin Rong; Karolinska Institutet; Karolinska Institutet; []
   Keywords : bone metabolism; breast cancer; calcitonin; calcium; exercise; lanthanide; milk; neonate; osteoporosis; parathyroid hormone-related protein; parturition; polymerase chain reaction; time-resolved fluorometry;

   Abstract : The present studies were performed to elucidate several physiological and clinical questions of calcitonin (CT) and parathyroid hormone-related protein (PTHrP) such as: a) Does age influence the basal and calcium-stimulated levels and circulating molecular forms of CT in healthy females? b) Are osteoporotic patients lacking circulating monomeric CT? c) How is salmon CT (sCT) absorbed and cleared during treatment of diseases? d) Is there any effect of acute physical activity on circulating CT, PTH, PTHrP and bone metabolic markers? e) Is there an absorbance of PTHrP in milk by the neonate? and f) Are there any interactions between CT and PTHrP? In addition, by use of time-resolved dissociation and enhancement lanthanide fluorometry, the effort was put to develop two-site immunofluorometric assays (IFMA) for sCT and PTHrP as well as a quantitative competitive PCR (QC-PCR) for measuring PTHrP mRNA and use these methods in some of the investigations. Heterogeneity of CT forms in serum was disclosed after immunoextraction, fast protein liquid chromatography (FPLC) and radioimmunoassay (RIA) in healthy females and osteoporotic patients. READ MORE

5. 13. Tibial shaft fractures : An epidemiological and clinical study

   Author : Abbas Emami; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Tibial fractures; epidemiology; external fixation; infected nonunions; ultrasoundstimulation; serum bone markers; Kirurgi; Surgery; Kirurgi; Orthopaedics; ortopedi;

   Abstract : The epidemiological features of tibial shaft fractures were studied in Uppsala during two 5-year periods. The incidence decreased in men below 20 years of age in the late 1980's compared with the early 1970's (mostly due to a reduction of fractures sustained in traffic accidents), while the incidence increased in women over 80. READ MORE

6. 14. Water–fat separation in magnetic resonance imaging and its application in studies of brown adipose tissue

   Author : Jonathan Andersson; Joel Kullberg; Håkan Ahlström; Mark Lubberink; Kerstin Lagerstrand; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; brown adipose tissue; magnetic resonance imaging; water–fat signal separation; graph-cut; positron emission tomography; 18F-fludeoxyglucose; infrared thermography; machine learning; artificial neural networks; deep learning; convolutional neural networks; Radiology; Radiologi;

   Abstract : Virtually all the magnetic resonance imaging (MRI) signal of a human originates from water and fat molecules. By utilizing the property chemical shift the signal can be separated, creating water- and fat-only images. READ MORE

7. 15. Bone Metabolism in Men

   Author : Peter Gillberg; Olof Johnell; Uppsala universitet; []
   Keywords : Medical sciences; Male osteoporosis; Bone mineral density; Growth hormone; Insulin-like growth factors; Sex hormones; Growth hormone replacement; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Abstract : In this thesis, the importance of the growth hormone (GH)/insulin-like growth factor (IGF) system and sex steroids for male bone metabolism has been investigated, and the effects of continuous low dose GH replacement in GH deficient (GHD) adults. In a population-based sample of men, positive correlations were found between bone mineral density (BMD) and IGF-I, IGF-II, IGF binding protein (IGFBP)-3 and the testosterone/sex hormone binding globulin (SHBG) ratio. READ MORE