Search for dissertations about: "Osteoklast"

Found 3 swedish dissertations containing the word Osteoklast.

  2. 1. Development of Novel Therapies, Models, and Biomarkers for Osteoclast-Related Diseases

    Author : Henrik Löfvall; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osteopetros; Biomarkör; Cellodling; Extracellulär matrix ECM ; Osteoklast; Osteoclast; Biomarker; Cell culture; Osteopetrosis; Gene Therapy; Extracellular matrix ECM ;

    Abstract : Osteoclasts are derived from hematopoietic stem cells (HSCs) and form upon stimulation of osteoclast precursors by macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor κΒ ligand (RANKL). Osteoclasts resorb bone by secreting hydrochloric acid, matrix metalloproteinases (MMPs) and cathepsin K. READ MORE

  4. 2. Aspects of oral implant technology and osseointegration

    Author : Rainde Naiara Rezende de Jesus; Malmö universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomaterials; oral implants; surface topography; surface roughness; surface energy; surface wettability; hydrophilicity; macrogeometry; implant body; thread design; surgical protocol; oversized drilling; osseointegration; bone-to-implant contact; bone density; primary implant stability; insertion torque; removal torque; removal energy; connection stiffness; osteoclasts; RAW264.7 cells; gene expression;

    Abstract : Behandling med käkbensförankrade tandimplantat är en vanlig metod för att ersätta förlorade tänder hos helt och partiellt tandlösa patienter. Trots att implantatbehandling uppvisar en långsiktigt hög lyckande- och överlevnadsfrekvens (90–95% efter 10 år) så förekommer implantatförluster och marginal benförlust kring implantaten under det första året efter insättning och/eller belastning, vilket kan försämra det estetiska resultatet. READ MORE

  5. 3. Bisphosphonates for orthopedic applications. Studies in rat models

    Author : Jörgen Åstrand; Lund Ortopedi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatology; Kirurgi; ortopedi; traumatologi; orthopaedics; Surgery; topical treatment; osteonecrosis; bone graft resorption; prosthetic loosening; Bisphosphonates; osteoclasts;

    Abstract : Prosthetic loosening, bone graft resorption and osteonecrosis are examples of problems in orthopedic surgery caused by or augmented by bone resorption. Bone resorption is caused by osteoclasts. Osteoclasts can be inactivated with biphosphonates, a drug in clinical use against osteoporosis and osteolytic tumors. READ MORE