Search for dissertations about: "Oxaliplatin side effect"

Showing result 1 - 5 of 6 swedish dissertations containing the words Oxaliplatin side effect.

  2. 1. Chemoradiation in Gastrointestinal Cancer

    Author : Adalsteinn Gunnlaugsson; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biliary tract cancer; capecitabine; cholangiocarcinoma; chemoradiation; colon cancer; enteritis 5-fluorouracil; gallbladder cancer; oxaliplatin; pancreatic cancer; rectal cancer.;

    Abstract : Locally advanced inextirpable gastrointestinal cancer has poor prognosis and is associated with high morbidity. One treatment option is to use radiotherapy, often combined with chemotherapy (chemoradiation), either as preoperative treatment to facilitate surgery or in the palliative setting to relieve symptoms. READ MORE

  4. 2. Biotransformation of the antineoplastic drug oxaliplatin : importance for effects and side effects

    Author : Elin Jerremalm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Oxaliplatin is a platinum-based cytostatic drug. It is used in combination with 5-fluorouracil and leucovorin for palliative and adjuvant treatment of metastatic colorectal cancer. READ MORE

  5. 3. Chemical transformation of the anticancer drug oxaliplatin

    Author : Elin Jerremalm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Oxaliplatin is a new platinum based cytostatic drug. It is used in combination with 5-fluorouracil and leucovorin, both as palliative and adjuvant treatment of metastatic colorectal cancer. Various biotransformation products are formed non-enzymatically after oxaliplatin administration. READ MORE

  6. 4. Pharmacokinetics and inner ear transport of cisplatin

    Author : Victoria Hellberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Cisplatin is a commonly used platinum anti-cancer drug. Regrettably cisplatin has dose-limiting ototoxic side effects, e.g. the drug can induce an irreversible hearing loss. READ MORE

  7. 5. Molecular aspects on voltage-sensor movement

    Author : Amir Broomand; Fredrik Elinder; Guiscard Seebohm; Linköpings universitet; []
    Keywords : Potassium channels; voltage-gated; chemistry; metabolism; physiology; patch-clamp techniques; oocytes; MEDICINE; MEDICIN;

    Abstract : Voltage-gated ion channels are fundamental for electrical signaling in living cells. They are composed of four subunits, each holding six transmembrane helices, S1-S6. Each subunit contains a voltage-sensor domain, S1-S4, and a pore domain, S5-S6. READ MORE