Search for dissertations about: "Pınar Akçakaya"

Found 1 swedish dissertation containing the words Pınar Akçakaya.

2. 1. Molecular mechanisms of imatinib resistance in gastrointestinal stromal tumor with focus on microRNAs

   Author : Pınar Akçakaya; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Gastrointestinal stromal tumor (GIST) is mainly initialized by mutations in receptor tyrosine kinase genes KIT or PDGFRA. The development of imatinib, a small molecule inhibitor that targets these tyrosine kinase receptors, remarkably improved patient outcome. READ MORE