Search for dissertations about: "P Holmberg"

Showing result 1 - 5 of 11 swedish dissertations containing the words P Holmberg.

  2. 1. Battling Bacterial Biofilm - antibiotic regimens targeting Grampositive pathogens in biofilm

    Author : Anna Holmberg; Sektion III; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biofilm; antibiotic susceptibility; prosthetic joint infection; MBEC; Enterococcus faecalis; Enterococcus faecium; Propionibacterium acnes.;

    Abstract : AbstractBacteria in most environments encase themselves in a hydrated matrix of polysaccharide and protein, forming organized communities called biofilms. In the biofilm bacteria are protected against hostile environments. Biofilms are important clinically because of their persistence despite host defence and their recalcitrance to antimicrobials. READ MORE

  4. 2. Trauma Care - Implementation, Evaluation and Validation

    Author : Lina Holmberg; Kevin Mani; Fredrik Linder; Anders Wanhainen; Håkan Andréasson; Shariq S. Raza; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Trauma triage criteria; undertriage; validation; trauma registry; accuracy; trauma trends; penetrating trauma; mortality.;

    Abstract : Trauma is a major cause of death and morbidity in all ages, which makes continuous improvement of trauma care a high priority. During the last decades, Sweden’s trauma system has evolved with initiation of a national trauma registry (SweTrau) in 2011 and the Swedish National Trauma Triage criteria (SNTTC) in 2017. READ MORE

  5. 3. Invasive intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma : a comparison in clinicopathology and long-term outcome

    Author : Marcus Holmberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: The resections for both pre-malignant and invasive intraductal papillary mucinous neoplasm (inv-IPMN) have increased the last decades. Long term outcome, and the impact of adjuvant chemotherapy, non-regional lymph node status and recurrence pattern on overall survival (OS) is known for conventional pancreatic ductal adenocarcinoma (PDAC), but not so for inv-IPMN. READ MORE

  6. 4. Reduced ROS production triggers arthritis / The role of T cells in arthritis pathogenesis

    Author : Jens Holmberg; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Spleen and lymph nodes Inflammation Reactive oxygen species T cells MHC; serology; Immunology; Immunologi; serologi;

    Abstract : The aim of this thesis is to defend a novel mechanism that triggers arthritis susceptibility in both rats and mice through reduced production of reactive oxygen species (ROS), but also to introduce a novel model for chronic relapsing arthritis. Five papers are included, all of which employ animal models for rheumatoid arthritis and one that also uses animal models for multiple sclerosis. READ MORE

  7. 5. Mitotic Kinesin-Like Protein 1 (MKLP1/KIF23) in hereditary congenital dyserythropoietic anemia type III and in cancer

    Author : Ann-Louise Vikberg; Irina Golovleva; Monica Holmberg; Masanori Mishima; Pontus Aspenström; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alternative splicing; Cell division; COPI; Congenital dyserythropoietic anemia; Cytokinesis; Gene expression; KIF23 protein human; Cancer; MKLP1 protein mouse; Mutation; medicinsk genetik; Medical Genetics;

    Abstract : A hereditary form of autosomal dominant congenital dyserythropoietic anaemiatype III (CDA III) has been reported in four families from Sweden, Argentina, Cuba and USA. CDA III patients might experience signs of mild anaemia and some of them need occasional blood transfusions. READ MORE