Search for dissertations about: "P-selectin."

Showing result 31 - 35 of 52 swedish dissertations containing the word P-selectin..

  1. 31. Shock wave effects on the vascular endothelium

    Author : Anders Sondén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Shock waves; cavitation; explosions; high-energy missile trauma; ESWL; laser; endothelial cells; cell membrane damage; cytoskeleton; adhesion molecules; reactive oxygen species;

    Abstract : A shock wave is a pressure wave with high amplitude and a velocity above sound. Man is exposed to shock waves (SWs) in connection with trauma, e.g. explosions and high-energy missiles and medical treatments such as extracorporeal lithotripsy (ESWL). READ MORE

  2. 32. Trypsinogen and neutrophil activation in acute Pancreatitis

    Author : Hannes Hartman Magnusson; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute pancreatitis; trypsinogen activation; adhesion; neutrophil extracellular traps;

    Abstract : Background and aims: Acute pancreatitis (AP) is a common condition characterized by premature protease activation, abdominal pain and leakage of pancreatic enzymes to the circulation. Approximately 10% develop systemic inflammation and persistent organ failure. READ MORE

  3. 33. Experimental and Clinical Studies on Platelet Receptors in Cardiovascular Disease

    Author : Oscar Braun; Kardiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; inflammation; athersosclerosis; platelets; thrombosis; Cardiovascular system; Kardiovaskulära systemet;

    Abstract : The crucial role of platelets in maintaining primary hemostais has been evident for a long time and there is now also mounting evidence for their involvement in inflammation. In combination with aspirin, inhibition of the platelet P2Y12 ADP receptor with clopidogrel has become a cornerstone in the antiplatelet in acute coronary syndromes. READ MORE

  4. 34. Leukocytes and Coronary Artery Disease : Experimental and Clinical Studies

    Author : Eva Lindmark; Peter Kierulf; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Tissue factor; monocytes; platelets; cytokines; endothelial cells; unstable coronary artery disease; coagulation; inflammation; biochemical markers; IL-6; risk stratification; Biokemi; Biochemistry; Biokemi; Clinical Chemistry; klinisk kemi;

    Abstract : Tissue factor (TF) is the initiator of the coagulation cascade. Monocytes do not normally express TF, but can be induced to do so by certain stimuli. Aberrant TF expression is important in the thrombotic complications of bacterial sepsis, certain malignancies and coronary artery disease (CAD). READ MORE

  5. 35. Studies on Cell Injury Induced by Hypoxia-Reoxygenation and Oxidized Low Density Lipoprotein : With Special Reference to the Protectiove Effect of Mixed Tocopherols, Omega-3 Fatty Acids and Transforming Growth Factor-beta1

    Author : Hongjiang Chen; Tom Saldeen; Christer Sylven; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Tocopherols; fish oil; TGF-β1; NOS; adhesion molecules; MMPs; PKB; MAPK; H-R; Ox-LDL; Myocytes; HCAECs; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Abstract : Hypoxia-reoxygenation (H-R) injury is an important clinical phenomenon in patients with coronary artery disease (CAD). Endothelial injury is a critical step in the initiation and progression of atherosclerosis. Therefore, endothelial and cardiomyocyte protection has been considered an effective step in prevention and treatment of CAD. READ MORE