Search for dissertations about: "P. Andreas Jonsson"

Found 3 swedish dissertations containing the words P. Andreas Jonsson.

  2. 1. Superoxide dismutase 1 and amyotrophic lateral sclerosis

    Author : P. Andreas Jonsson; Stefan L. Marklund; David R. Borchelt; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; aggregates; ALS; amyotrophic lateral sclerosis; cerebrospinal fluid; disulfide-reduced; inclusions; misfolded; protective factor; SOD1; transgenic; Neurovetenskap; Neurology; Neurologi; Clinical Chemistry; klinisk kemi;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease affecting motor neurons in the spinal cord, brain stem and motor cortex, leading to paralysis, respiratory failure and death. In about 5% of ALS cases, the disease is associated with mutations in the CuZn-superoxide dismutase (hSOD1) gene. READ MORE

  4. 2. Towards novel antibacterials : Synthesis and identification of natural product inspired inhibitors of Chlamydia trachomatis and development of chemical probes targeting virulence of Pseudomonas aeruginosa

    Author : Michael Saleeb; Mikael Elofsson; Anna Linusson Jonsson; Andreas Kirschning; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibacterials; antibiotics; small molecules; natural products; benzofuran; dihydrobenzofuran; the type III secretion system; Pseudomonas aeruginosa; Chlamydia trachomatis; phenotypic screening; high-throughput screening; surface plasmon resonance; drug discovery; bacterial toxins; enzyme inhibitors; organisk kemi; Organic Chemistry;

    Abstract : Antibiotic resistance has evolved significantly to become one of the serious threats to public health today. Yet, the pipeline of new antibiotics is drying up and is lagging behind the challenging needs. READ MORE

  5. 3. Predicting Ecosystem Response from Pollution in Baltic Archipelago areas using Mass-balance Modelling

    Author : Olof Magnus Karlsson; Andreas Bryhn; Lars Håkanson; Per Jonsson; Mikael Malmaeus; Kristoffer Naes; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Baltic Sea; archipelagos; aquatic ecosystems mass-balance modelling; sediment-water dynamics; phosphorus; dioxins; PCDD Fs; Other earth sciences; Övrig geovetenskap; Earth Science with specialization in Environmental Analysis; Geovetenskap med inriktning mot miljöanalys;

    Abstract : Baltic archipelago areas have high nature values despite being polluted from various antrophogenic activities within the Baltic Sea catchment area and from long-range transport of airborne substances. The discovery of environmental problems in the Baltic Sea in the 1960s led to countermeasures that gradually gave results in reducing the toxic pollution, e. READ MORE