Search for dissertations about: "PACAP"

Showing result 11 - 15 of 25 swedish dissertations containing the word PACAP.

  2. 11. Pathophysiology and treatment of defective insulin secretion in diabetes

    Author : Anders Rosengren; Diabetes - öpatofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic beta-cells; stem cells; genetics; exocytosis; Adra2a; PACAP; GLP-1; Physiology; Fysiologi; secreting systems; Endocrinology; diabetology; Endokrinologi; insulin secretion; Diabetes mellitus; sekretion; diabetologi;

    Abstract : Defective insulin secretion is a central feature in diabetes mellitus and results from reduced pancreatic beta-cell mass as well as aberrant beta-cell function. The pathophysiology of diabetes is incompletely known, but a strong hereditary component is suggested. READ MORE

  4. 12. Histamine and chromogranin A-derived peptides in rat stomach ECL cells

    Author : Per Norlén; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacy; pharmacognosy; Pharmacological sciences; CGRP adrenaline; galanin; VIP; PACAP; somatostatin; gastrin; microdialys; pancreastatin; chromogranin A; histamine; ECL cell; rat stomach; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : The ECL cells constitute the predominant endocrine cell population of the stomach. They secrete histamine which is a major stimulator of acid secretion. Chormogranin A (CgA)-derived peptides, such as pancreastatin, are co-secreted with histamine. READ MORE

  5. 13. Nitric Oxide Synthase in Pancreatic Islets During Trauma and Parenteral Feeding

    Author : Saleem Qader; Islet cell physiology; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi; Gastroenterologi; Gastro-enterology; Pancreatitis; Ghrelin; TPN; cNOS; iNOS; PACAP; VIP; cAMP; Pancreatic islets; Insulin secretion;

    Abstract : The influence of trauma (acute pancreatitis) or total parenteral nutrition (TPN) on pancreatic islet hormone secretion in relation to islet expression of inducible nitric oxide synthase (iNOS) was investigated. Acute pancreatitis resulted in an impaired glucose-stimulated insulin secretion (GSIS) which was found to be parallelled by a marked expression of iNOS and an exaggerated NO production in the pancreatic islets. READ MORE

  6. 14. Pituitary Adenylate Cyclase Activating Peptide (PACAP): An Experimental Study On the Expression and Regulation in the Peripheral Nervous System

    Author : Kristian Moller; Neuroendokrin cellbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytokemi; histokemi; Histologi; vävnadskultur; Histology; cytochemistry; histochemistry; tissue culture;

    Abstract : This thesis deals with PACAP and PACAP type-1 receptors in the sensory and autonomic parts of the peripheral nervous system. In the rat, PACAP is expressed in small-sized sensory neurons and in C-fibers. READ MORE

  7. 15. Regulation of lipid metabolism in rat and 3T3-L1 adipocytes; Cross-talk between Insulin, the neuro-peptides PACAP/VIP and with B1-integrins

    Author : Lina Åkesson; Celiaki och diabetes; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; secreting systems; Endocrinology; obesity; Insulin; diabetes;

    Abstract : Type 2 Diabetes is a disorder that increases globally, but mainly in the western world. One of the hallmarks of Type 2 diabetes is insulin resistance in the target tissues of insulin action (adipose tissue, liver and skeletal muscle). In addition, most patients with Type 2 diabetes are obese. READ MORE