Search for dissertations about: "PAI-1"

Showing result 6 - 10 of 85 swedish dissertations containing the word PAI-1.

  2. 6. Extracellular matrix remodelling proteases in acute appendicitis and their impact on appendiceal perforation

    Author : Anna Solberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; appendicitis; perforation; extracellular matrix; MMP-9; TIMP-1; uPA; PAI-1;

    Abstract : Abstract Background Appendicitis is associated with varying degradation of extracellular matrix involved in tissue injury. The principal aim of this study was to investigate whether immunoreactive techniques could illustrate the course and severity of appendicitis and separate the different inflammatory grades, phlegmonous, gangrenous and perforated appendicitis, from each other and from uninflamed appendix. READ MORE

  4. 7. Biochemical and Epidemiological Studies of Early-Onset and Late-Onset Pre-Eclampsia

    Author : Anna-Karin Wikström; Matts Olovsson; Ulf Eriksson; Solveig Norden-Lindeberg; Göran Berg; Uppsala universitet; []
    Keywords : Obstetrics and gynaecology; pre-eclampsia; proteinuria; albumin-creatinine ratio; ischaemic heart disease; angiogenesis; sFlt1; oxidative stress; isoprostane; PAI-1; PAI-2; Obstetrik och kvinnosjukdomar;

    Abstract : Biochemical and epidemiological aspects of pre-eclampsia were investigated, with the main focus on possible pathophysiological differences between early-onset and late-onset disease.In pre-eclamptic women poor correlation was found between albumin-creatinine ratio (ACR) in a random urine sample and total amount of albumin in a 24-hour urine collection. READ MORE

  5. 8. Strategies for postoperative adhesion control

    Author : Kristina Falk; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adhesion formation; adhesion prevention; experimental model; mouse; human; fibrinolysis; bioadhesion; cellulose; hydrophobic modification; t-PA; PAI-1; proCPU; TAFI;

    Abstract : Introduction: Abdominal surgery almost inevitably leads to adhesion formation, which often results in substantial morbidity. The formation of postsurgical adhesions seems to be determined by the balance of fibrin deposition and degradation in an early phase of peritoneal tissue repair. READ MORE

  6. 9. Hyperbaric oxygen. Effects on ischemia-reperfusion

    Author : Johan Tjärnström; Göteborgs universitet; []
    Keywords : fibrinolysis; f-MLP; human; hyperbaric oxygen; neutrophils; normobaric; PAI-1; PMA; rat; t-PA; trauma; uPA;

    Abstract : Treatment with hyperbaric oxygen (HBO2) is controversial when treating other disorders than decompression sickness. However, HBO2 is a treatment modality that has gained recognition in certain ischemia-reperfusion situations. READ MORE

  7. 10. Experimental and Clinical Studies of Oxidative Stress in Pre-Eclampsia

    Author : Peppi Nash; Ulf Eriksson; Matts Olovsson; Leif Jansson; Lucilla Poston; Uppsala universitet; []
    Keywords : Obstetrics and gynaecology; Pre-eclampsia; Oxidative stress; Diabetes; Placenta; Rat; Antioxidants; Suramin; Vitamin E; Vitamin C; PAI-1; PAI-2; Obstetrik och kvinnosjukdomar;

    Abstract : Impaired placentation and oxidative stress are proposed to play major roles in the pathogenesis of pre-eclampsia (PE). It has recently been pointed out that PE might be more than one disease and may have several different pathogeneses. READ MORE