Search for dissertations about: "PALLADIUM-CATALYZED REACTION"

Showing result 1 - 5 of 46 swedish dissertations containing the words PALLADIUM-CATALYZED REACTION.

  2. 1. New Methods for the Synthesis of 3-Substituted 1-Indanones : A Palladium-Catalyzed Approach

    Author : Anna Arefalk; Anders Hallberg; Mats Larhed; Juan Carlos Carretero; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Heck; palladium; indanone; annulation; microwave heating; triflate; sulfinyl imine; HIV-1 protease inhibitor; Organisk kemi; Organic chemistry; Organisk kemi;

    Abstract : In medicinal chemistry, there is a constant need for new preparative methods, both to make the synthesis process more effective, and to increase the accessibility to a wide variety of compounds. A number of different approaches can be used to attain these goals. READ MORE

  4. 2. Palladium-catalyzed lignin valorization : Towards a lignin-based biorefinery

    Author : Maxim Galkin; Joseph Samec; Rafael Luque; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Lignin; Heterogeneous Catalysis; Palladium; Biomass; Depolymerization; Reduction; Oxidation; Biorefinery; Transfer Hydrogenolysis; Organic Chemistry; Organisk kemi;

    Abstract : The work described in this thesis focuses on the cleavage of the β-O-4′ bond, which is the most abundant interunit linkage in the lignin polymer.In the first part, three methods based on palladium catalysis have been developed and their applicability has been verified using lignin model compounds. READ MORE

  5. 3. New Methods for the Synthesis of Vicinal Stereocenters : Palladium-Catalyzed Domino Reactions and Asymmetric Transfer Hydrogenation

    Author : Brinton Seashore-Ludlow; Somfai Peter; Kevin Booker-Milburn; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; asymmetric synthesis; domino reactions; palladium-catalyzed reactions; oxindoles; amino alcohols;

    Abstract : In this thesis the synthesis of vicinal stereocenters is investigated in two distinct contexts, namely the construction of 3,3-disubstituted oxindoles and the synthesis of b-hydroxy-a-amino acids. Both scaffolds are prevalent in a range of natural products and biologically relevant compounds and, therefore, methods for their synthesis are of great import. READ MORE

  6. 4. Palladium-Catalyzed Nucleophilic Substitution of Alcohols : Mechanistic Studies and Synthetic Applications

    Author : Supaporn Sawadjoon; Joseph Samec; Takao Ikariya; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; palladium; nucleophilic substitution; mechanism; Organic Chemistry; Organisk kemi;

    Abstract : This thesis deals with the palladium-catalyzed nucleophilic substitution of π-activated alcohols in which the C–O bond of a non-manipulated hydroxyl group is cleaved. The thesis is divided in two chapters describing two different catalytic systems. READ MORE

  7. 5. Palladium-Catalyzed Carbonylation and Arylation Reactions

    Author : Jonas Sävmarker; Mats Larhed; Gary Molander; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; palladium; carbonylation; styrene; amidine; aryl ketones; aryl sulfinates; ESI-MS; aryltrifluoroborates; Organic Pharmaceutical Chemistry; Organisk farmaceutisk kemi;

    Abstract : Palladium-catalyzed reactions have found widespread use in contemporary organic chemistry due to their impressive range of functional group tolerance and high chemo- and regioselectivity. The pioneering contributions to the development of the Pd-catalyzed C-C bond forming cross-coupling reaction were rewarded with the Nobel Prize in Chemistry in 2010. READ MORE