Search for dissertations about: "PAP"

Showing result 16 - 20 of 74 swedish dissertations containing the word PAP.

  2. 16. Development of Novel Therapies, Models, and Biomarkers for Osteoclast-Related Diseases

    Author : Henrik Löfvall; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osteopetros; Biomarkör; Cellodling; Extracellulär matrix ECM ; Osteoklast; Osteoclast; Biomarker; Cell culture; Osteopetrosis; Gene Therapy; Extracellular matrix ECM ;

    Abstract : Osteoclasts are derived from hematopoietic stem cells (HSCs) and form upon stimulation of osteoclast precursors by macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor κΒ ligand (RANKL). Osteoclasts resorb bone by secreting hydrochloric acid, matrix metalloproteinases (MMPs) and cathepsin K. READ MORE

  4. 17. Expression and post-translational modification of purple acid phosphatase in insect and mammalian cells

    Author : Yunling Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Purple acid phosphatase (PAP) is an acidic metallohydrolase that contain a binuclear iron center in its active site. In mammals, this enzyme is also referred to as tartrate-resistant acid phosphatase (TRAPs), uteroferrin or type 5 acid phosphatase. READ MORE

  5. 18. Regulation of tartrate-resistant purple acid phosphatase by proteolytic processing in rat

    Author : Jenny Ljusberg-Sjölander; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Purple acid phosphatase; enzyme catalysis; proteolytic processing;

    Abstract : Purple acid phosphatase (PAP) is an iron-containing binuclear acid metallohydrolase with a characteristic purple colour, also referred to as tartrate-resistant acid phosphatase (TRAP), uteroferrin or type 5 acid phosphatase. PAP is highly expressed in osteoclasts and has a role in bone resorption. READ MORE

  6. 19. Physical activity on prescription with access to counsellor support implemented in routine care : Healthcare and patient perspectives

    Author : Pia Andersen; Per Nilsen; Sara Holmberg; Lena Lendahls; Lars Weinehall; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physical activity on prescription; Counselling; Counsellor; Health care; Patients;

    Abstract : Background: The Swedish PAP (physical activity on prescription) programme FaR®, introduced in 2001, has been adopted by all Swedish regions, which are responsible for provision of healthcare in Sweden. Several studies have shown positive outcomes of the Swedish PAP on patients’ physical activity and other health-related outcomes. READ MORE

  7. 20. Physical activity on prescription in primary care. Impact on physical activity level, metabolic health and health-related quality of life, and its cost-effectiveness - a short- and long-term perspective

    Author : Stefan Lundqvist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Primary health care; Physical activity; Physical activity on prescription; Metabolic syndrome; Health related quality of life; Quality of life; Health behavior; Life style; Correlates of physical activity; Predictive factor; Health economics; Cost-effectiveness; Cost-Benefit Analysis;

    Abstract : Non-communicable diseases (NCDs) are the leading cause of death globally and one of the major health challenges of the 21st century. In Sweden, NCDs are estimated to account for 90 % of all deaths. READ MORE