Search for dissertations about: "PBMC"

Showing result 1 - 5 of 117 swedish dissertations containing the word PBMC.

  1. 1. Molecular characterization of the hepatitis C virus core protein

    Author : Priya Devi; Anders Bergqvist; Björn Olsen; Tanel Punga; Gerald McInerney; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; HCV; core protein; SHP-1; CpG methylation; bisulfite sequencing; NGS; PBMC; Ca2 NFAT; strand-specific RT qPCR; Klinisk virologi; Clinical Virology; Infektionssjukdomar; Infectious Diseases; Mikrobiologi; Microbiology; Medical Virology; Medicinsk virologi;

    Abstract : Hepatitis C virus (HCV) is an RNA virus that causes chronic infection, which can lead to hepatocellular carcinomas in humans. Besides liver diseases, the chronic HCV infection causes a broad spectrum of extrahepatic complications such as lymphoproliferative, metabolic and autoimmune disorders. READ MORE

  2. 2. The role of the alpha 7 nicotinic acetylcholine receptor in inflammation and brain injury

    Author : Maria Hammarlund; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha 7 nicotinic acetylcholine receptor; inflammation; brain injury; CHRNA7; CHRFAM7A; stroke; hypoxia ischemia; neonatal encephalopathy; human; PBMC;

    Abstract : The alpha 7 nicotinic acetylcholine receptors (α7nAChR) are expressed in the nervous system as well as on peripheral immune cells where it participates in the cholinergic anti-inflammatory pathway. Inflammation is a common component in the pathology of many diseases and injuries, including brain damage. READ MORE

  3. 3. Immunological mechanisms involved in seasonal pollen allergy and allergen-specific immunotherapy

    Author : Robert Movérare; Uppsala universitet; []
    Keywords : Medical sciences; Allergy; birch pollen; IFN-g; IgE; IgG; IgG4; IL-4; IL-5; IL-10; IL-13; immunotherapy; PBMC; rush immunotherapy; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; lungmedicin; Lung Medicine;

    Abstract : Th1/Th2-like T-cell responses were studied by stimulating peripheral blood mononuclear cells (PBMCs) with allergens or antigens followed by restimulation with mitogens to induce high cytokine synthesis. Allergen-stimulation in vitro induced Th2-skewed cytokine synthesis by PBMCs from birch-pollen-allergic patients. READ MORE

  4. 4. Epidemiological and immunological studies of environmental mycobacteria - with focus on Mycobacterium abscessus

    Author : Bodil Jönsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Bacteriology; Immunology; Epidemiology; Mycobacteria; Mycobacterium abscessus; Colony morphology; Mycobacterial lipids; Cystic fibrosis; PFGE; Human PBMC; Cytokine; Phagocytosis;

    Abstract : Mycobacterium avium, M. abscessus and M. gordonae are three mycobacterial species that are ubiquitous in the environment. M. READ MORE

  5. 5. The role of Malassezia in the pathogenesis of atopic eczema/dermatitis syndrome

    Author : Catharina Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Atopic dermatitis; atopic eczema dermatitis syndrome; Malassezia; Pityrosporum; T-cells; PBMC proliferation; cytokines; ELISPOT; TCRVB; IgE; skin prick test; atopy patch test;

    Abstract : Atopic eczema/dermatitis syndrome (AEDS) is a chronically relapsing skin disease, which is often associated with elevated levels of serum lgE. The immunopathology of AEDS is at present unclear, but it is known that lymphocytes infiltrating the AEDS lesions are predominantly of the CD4+ T helper phenotype. READ MORE