Search for dissertations about: "PBN"
Showing result 1 - 5 of 22 swedish dissertations containing the word PBN.
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1. The role of reactive oxygen species in traumatic brain injury : Experimental studies in the rat
Abstract : Traumatic brain injury (TBI) is a major cause of mortality and disability. As common sequelae in survivors of TBI are disabling functional, emotional and cognitive disturbances, improved treatment of TBI patients is urgently needed. At present, no neuroprotective pharmacological treatment exists. READ MORE
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2. Experimental cardiopulmonary cerebral resuscitation : with special reference to cerebral eicosanoid production and free radical scavengers
Abstract : Reperfusion injury after restoration of spontaneous circulation (ROSC) is often considered one of the predominant factors in determining neurological outcome in cardiac arrest. Therefore one of the main targets of experimental and clinical studies has been to mitigate this reperfusion injury. READ MORE
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3. Mechanisms of Brain Damage Following Focal Cerebral Ischemia: Changes in Ion Homeostasis and the Importance of Free Radical Formation
Abstract : In this thesis mechanisms of neuronal damage were investigated in an experimental stroke model i.e focal ischemia. The influence of SD-induced calcium transients on neuronal damage were studied in animals with reduced energy supply. READ MORE
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4. Survival of Cultured and Grafted Embryonic Dopaminergic Neurones - Effects of hypothermia and prevention of oxidative stress
Abstract : Transplantation of embryonic dopaminergic neurones can ameliorate symptoms in Parkinson’s disease, but a major obstacle for clinical transplantations to overcome is the low survival (typically 5-10%) of implanted nigral neurones. If cell death in nigral grafts can be prevented, less embryonic tissue would be needed per transplantation session and hence more patients could receive intracerebral grafts as a therapy for Parkinson’s disease. READ MORE
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5. Novel Interventions in Cardiac Arrest : Targeted Temperature Management, Methylene Blue, S-PBN, Amiodarone, Milrinone and Esmolol, Endothelin and Nitric Oxide In Porcine Resuscitation Models
Abstract : It is a major clinical problem that survival rates after out-of-hospital cardiac arrest have not markedly improved during the last decades, despite extensive research and the introduction of new interventions. However, recent studies have demonstrated promising treatments such as targeted temperature management (TTM) and methylene blue (MB). READ MORE