Search for dissertations about: "PBTK"
Found 3 swedish dissertations containing the word PBTK.
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1. Computational methods for assessing chemical risk : focusing on toxicokinetic modelling in zebrafish (danio rerio)
Abstract : New chemicals are constantly produced and large data gaps exist on hazards of currently used industrial chemicals, stressing the need for rapid, ethically sound and cost-efficient hazard assessment methods. Traditional methods for effect assessment based on animal testing, do not meet these requirements and thus the toxicology field has been moving towards the development of new approach methodologies which include in vitro approaches but also computational methods. READ MORE
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2. Ethers as gasoline additives : toxicokinetics and acute effects in humans
Abstract : Ethers or other oxygen-containing compounds are used as replacements for lead in gasoline and to ensure complete combustion. Methyl tertiary-butyl ether (MTBE) is already in use world-wide and ethyl tertiary-butyl ether (ETBE) may be used increasingly in the future. READ MORE
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3. Fluorinated hydrocarbons used as refrigerants : toxicokinetics and effects in humans
Abstract : Hydrofluorocarbons (HFCs) and hydrochlorofluorocarbons (HCFCs) have replaced the chlorofluorocarbons (CFCs) in refrigeration installations and air-conditioning applications. As substitution progressed, some refrigeration mechanics experienced symptoms of inflammation. READ MORE