Search for dissertations about: "PCA in pharmaceutical analysis"
Showing result 1 - 5 of 6 swedish dissertations containing the words PCA in pharmaceutical analysis.
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1. Multivariate Synergies in Pharmaceutical Roll Compaction : The quality influence of raw materials and process parameters by design of experiments
Abstract : Roll compaction is a continuous process commonly used in the pharmaceutical industry for dry granulation of moisture and heat sensitive powder blends. It is intended to increase bulk density and improve flowability. READ MORE
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2. Multivariate design of molecular docking experiments : An investigation of protein-ligand interactions
Abstract : To be able to make informed descicions regarding the research of new drug molecules (ligands), it is crucial to have access to information regarding the chemical interaction between the drug and its biological target (protein). Computer-based methods have a given role in drug research today and, by using methods such as molecular docking, it is possible to investigate the way in which ligands and proteins interact. READ MORE
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3. Process analytical methods for monitoring of the film coating on pharmaceutical pellets and tablets using NIR spectrometry and image analysis
Abstract : Pharmaceutical tablets and pellets are often covered with a coating. There is a need for methods that enable monitoring of the growth of such films during processing. Such analyses can be performed using process analytical chemical methods based on near infrared (NIR) diffuse reflectance spectrometry. It provides with analyses that take only ca. READ MORE
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4. Multivariate Measurements and Chemical Imaging of Organic Compounds
Abstract : Chemical imaging is an emerging analytical technique, based on the interplay between, most often, spectroscopic measurements and advanced evaluation methodology. With this we can study the distribution of chemical compounds in different compartments, such as individual cells and pharmaceutical tablets. READ MORE
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5. Multivariate spectroscopic methods for the analysis of solutions
Abstract : In this thesis some multivariate spectroscopic methods for the analysis of solutions are proposed. Spectroscopy and multivariate data analysis form a powerful combination for obtaining both quantitative and qualitative information and it is shown how spectroscopic techniques in combination with chemometric data evaluation can be used to obtain rapid, simple and efficient analytical methods. READ MORE