Search for dissertations about: "PDZ array"

Found 2 swedish dissertations containing the words PDZ array.

  2. 1. Functional characterization of interactions between the flavivirus NS5 protein and PDZ proteins of the mammalian host

    Author : Karin Ellencrona; Magnus Johansson; Andrew Davidson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Tick-borne encephalitis virus TBEV ; West-Nile virus WNV ; Dengue virus DENV ; flavivirus; PDZ domains; ZO-2; ZO-1; RIMS2; Scribble; Interferon; JAK-STAT signaling; PDZ array; virus-host protein interaction; Genetics; Genetik; molekylärgenetik; Molecular Genetics;

    Abstract : Flaviviruses are found all over the world and affect and infect millions of people every year. Flavivirus infection can lead to severe clinical outcomes resulting in neuronal damages e.g. Tick-borne encephalitis virus (TBEV), or severe hemorrhagic fevers e. READ MORE

  4. 2. Functional details of human HtrA2 protease studied by NMR spectroscopy

    Author : Emelie E. Aspholm; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HtrA2; nuclear magnetic resonance; protein quality control; neurodegenerative disease; apoptosis;

    Abstract : Cells rely on an array of cellular machineries in the protein quality control system (PQC) to maintain the health of the collective proteome. The HtrA family of serine proteases are found in all kingdoms of life and function in the PQC by degrading damaged and aggregated proteins as well as by acting as molecular chaperones. READ MORE