Search for dissertations about: "PGE2 in cancer"

Showing result 21 - 25 of 30 swedish dissertations containing the words PGE2 in cancer.

  2. 21. Central Nervous System and Innate Immune Mechanisms for Inflammation- and Cancer-induced Anorexia

    Author : Johan Ruud; Anders Blomqvist; David Engblom; John-Olov Jansson; Linköpings universitet; []
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    Abstract : Anyone who has experienced influenza or a bacterial infection knows what it means to be ill. Apart from feeling feverish, experiencing aching joints and muscles, you lose the desire to eat. Anorexia, defined as loss of appetite or persistent satiety leading to reduced energy intake, is a hallmark of acute inflammatory disease. READ MORE

  4. 22. Studies of the role of the cathelicidin peptide LL-37 in epithelial biology

    Author : Clara Ibel Chamorro Jimenez; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : The biology of epithelial immunity as well as of tissue repair is complex and highly regulated. A variety of molecules, cell types, and biological processes such as, cell differentiation, proliferation and migration, programmed cell death and antimicrobial mechanisms contribute to maintaining a balance between tissue damage and tissue repair. READ MORE

  5. 23. The destiny of natural killer cells in the tumor microenvironment : to be suppressed or activated?

    Author : Dhifaf Sarhan; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : In the mid-70s, the term “natural” was used based on the functional properties of NK cells where they recognize and lyse certain tumor cells without requirement of prior immunization. Although NK cells are “natural” in their targeting of tumors, their responses in the tumor microenvironment have been very challenging to determine. READ MORE

  6. 24. Novel therapy for neuroblastoma : focus on prostaglandin E2 and microsomal prostaglandin E synthases-1

    Author : Anna Kock; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Cancer is a major public health problem and to date cancer is one of the leading causes of death worldwide. Neuroblastoma is a malignant pediatric tumor of the sympathetic nervous system. Neuroblastoma is one of the most common and deadliest extra cranial tumors of childhood. READ MORE

  7. 25. Studies on anti-inflammatory and vasoactive effects of mPGES-1 inhibition

    Author : Julia Steinmetz-Späh; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Inflammation is the basis for various serious illnesses such as rheumatic diseases, cardiovascular diseases, and cancer. Prostaglandin E2 (PGE2) is a pro-inflammatory lipid mediator produced by cyclooxygenases (COX1/2) and the microsomal prostaglandin E synthase 1 (mPGES-1). READ MORE