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Showing result 1 - 5 of 123 swedish dissertations matching the above criteria.

  2. 1. Structural, Dynamic and Functional Studies of USP14 : A Proteasome-Associated Deubiquitinating Enzyme Regulating Protein Degradation

    Author : Johannes Salomonsson; Maria Sunnerhagen; Alexandra Ahlner; Eleonore von Castelmur; Pau Bernadó; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Ubiquitin-Specific Protease 14 (USP14) is a proteasome-associated deubiquitinating enzyme (DUB) involved in regulation of protein degradation and recycling of ubiquitin. USP14 consists of a Ubl domain connected to a USP domain via a flexible linker. READ MORE

  4. 2. Membrane lipids and their transfer proteins in β-cells

    Author : Beichen Xie; Olof Idevall-Hagren; Anders Tengholm; Jen Liou; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ca2 ; PKC; E-Syt1; TMEM24; ER-PM contact; PI 4; 5 P2; phosphoinositides; β-cell; insulin; optogenetics; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : Insulin secretion from β-cells is essential for glucose homeostasis and is often dysregulated in diabetes. Intracellular Ca2+ and membrane lipids cooperate to control insulin secretion with high spatial and temporal precision. READ MORE

  5. 3. AI-Based Methods For Improved Testing of Radio Base Stations : A Case Study Towards Intelligent Manufacturing

    Author : Cristina Landin; Amy Loutfi; Martin Längkvist; Sahar Tahvili; Brian Nielsen; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Computer Science; Datavetenskap;

    Abstract : Testing of complex systems may often require the use of tailored-made solutions, expensive testing equipment, large computing capacity, and manual implementation work due to domain uniqueness. The aforementioned test resources are expensive and time-consuming, which makes them good candidates to optimize. READ MORE

  6. 4. Free charge carrier properties in group III nitrides and graphene studied by THz-to-MIR ellipsometry and optical Hall effect

    Author : Nerijus Armakavicius; Vanya Darakchieva; Philipp Kühne; Stefan Zollner; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Development of silicon based electronics have revolutionized our every day life during the last five decades. Nowadays silicon based devices operate close to their theoretical limits that is becoming a bottleneck for further progress. READ MORE

  7. 5. Integrating domain knowledge into deep learning : Increasing model performance through human expertise

    Author : Niclas Ståhl; Göran Falkman; Alexander Karlsson; Gunnar Mathiason; Jonas Boström; Keith Downing; Högskolan i Skövde; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; INF301 Data Science; INF301 Data Science; Skövde Artificial Intelligence Lab SAIL ; Skövde Artificial Intelligence Lab SAIL ;

    Abstract : The research in this thesis is focused on how deep learning models can be designed and implemented to better emulate and integrate the heuristic reasoning process of human experts. Several case studies, within the domains of steel making and drug discovery, are conducted in order to evaluate the performance of these models, in comparison to models that do not consider human expert knowledge from the targeted domain. READ MORE