Search for dissertations about: "PHARMACY Biopharmacy"
Showing result 26 - 30 of 49 swedish dissertations containing the words PHARMACY Biopharmacy.
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26. Modelling of melanocortin receptors and their ligands
Abstract : Five subtypes of melanocortin receptors (MC1-MC5R) mediate a wide range of physiological actions, including control of skin tanning, inflammation and food intake. The natural ligands for these receptors are the melanocortins, which are linear peptides 11 to 39 amino acids long. READ MORE
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27. Interaction between chemicals and melanin : Role in the aetiology, diagnosis and treatment of melanoma
Abstract : The incidence of malignant melanoma has continually increased over the past decades and the prognosisis poor after dissemination of metastases. A conspicuous feature of melanocytes and melanoma cells is the production of melanin. READ MORE
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28. Clinical-Pharmacokinetic Aspects of Prolonged Effect Duration as Illustrated by β2-Agonists
Abstract : Regularity is a key element of maintenance drug treatment; compliance is crucial for treatment success. Once- or twice-daily intake of a drug is always easier to comply with than regimens requiring more frequent dosing. READ MORE
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29. Hemorphins and endomorphins
Abstract : In this thesis, two newly discovered endogenous opioid peptide families, the hemorphins and endomorphins, are investigated with emphasis on modulation of pain and inflammation. In addition, the presence of hemorphins in human biological fluids as well as the in vitro and in vivo processing ofLVV-hemorphin-7 in blood and brain is investigated. READ MORE
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30. Pharmacokinetics and Pharmacodynamics of Anti-Cancer Regimens : Emphasis on Busulphan and the Combination Therapies Epirubicin-Docetaxel and Fluorouracil-Epirubicin-Cyclophosphamide
Abstract : Although the main reason for the lack of distinct dose-response and -toxicity relationships for anti-cancer agents is due to variability in pharmacodynamics, variability in pharmacokinetics may also contribute. Hence, not only describing and quantifying the relationship between pharmacokinetics and dose-limiting toxicities, but characterising the pharmacokinetics and its associated variability are of obvious importance in the process of developing dosing strategies for anti-cancer regimens. READ MORE