Search for dissertations about: "PHARMACY Biopharmacy"
Showing result 6 - 10 of 49 swedish dissertations containing the words PHARMACY Biopharmacy.
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6. Cytochrome P450 enzymes in oxygenation of prostaglandin endoperoxides and arachidonic acid : Cloning, expression and catalytic properties of CYP4F8 and CYP4F21
Abstract : Cytochrome P450 (P450 or CYP) is an enzyme system involved in the oxygenation of a wide range of endogenous compounds as well as foreign chemicals and drugs. This thesis describes investigations of P450-catalyzed oxygenation of prostaglandins, linoleic and arachidoniacids. READ MORE
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7. Discovery of N-hydroxyguanidines as novel electron acceptors of xanthine oxidase : Potential new drugs for treatment of ischemia and reperfusion injury
Abstract : Xanthine oxidase (EC 1.1.3.22) is one of the major enzymatic sources of oxygen-derived free radicals. READ MORE
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8. Mutational analysis of melanocortin receptors 1 and 5
Abstract : The melanocortin receptor family includes five subtypes, named MC1R to MC5R. Melanocortin receptors are predominantly coupled to second messenger pathway of cyclic AMP through coupling to G-protein. This study is focused on structure-function relationship of MC1R and MC5R. READ MORE
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9. Enzymes in different pathways of bile acid biosynthesis
Abstract : Enzymes catalyzing side chain hydroxylations and dehydrogenation/isomerization in different pathways of bile acid biosynthesis were studied.Pig liver mitochondrial sterol 27-hydroxylase (CYP27A) was found to catalyze 24- and 25-hydroxylation of cholesterol in addition to the known 27-hydroxylation. READ MORE
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10. Characterization of resistance to quinolones, sulfonamide and trimethoprim in Campylobacter jejuni as well as to macrolides in the related bacterium, Helicobacter pylori
Abstract : Gastroenteritis caused by C. jejuni is usually a mild to moderate self-limiting disease. Treatment is recommended in some cases. In recent years, quinolones have been increasingly used to treat acute bacterial enteritis. READ MORE