Search for dissertations about: "PI-88"

Found 2 swedish dissertations containing the word PI-88.

  1. 1. Anti-herpes simplex virus activities of sulfomannan oligosaccharide PI-88 and disulfated cyclitols

    Author : Maria Ekblad; Göteborgs universitet.; Gothenburg University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; herpes simplex virus; antiviral drugs; viral glycoproteins; heparan sulfate mimetic; PI-88;

    Abstract : Herpes simplex virus (HSV) initiates invasion of human cells by binding to the cell surface heparan sulfate (HS) glycosaminoglycan chains. This step is mediated by the viral envelope glycoproteins gC and/or gB. READ MORE

  2. 2. Interaction of herpes simplex virus with cell surface glycosaminoglycans as a target for antiviral intervention

    Author : Kicki Bergefall; Göteborgs universitet.; Gothenburg University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HSV; glycoproteins; glycosaminoglycans; virus receptor; antiviral drugs;

    Abstract : Herpes simplex virus (HSV) infections in humans are predominantly manifested as oral cold sores or genital ulcers. As HSV infects cells by interaction with cell surface heparan sulfate (HS) and/or chondroitin sulfate (CS), the aim of the research work presented in this thesis was to explore the possibility of antiviral intervention with compounds that mimic HS or CS. READ MORE