Search for dissertations about: "PIM"

Showing result 11 - 15 of 38 swedish dissertations containing the word PIM.

  2. 11. Assessment of therapeutic targets in experimental models of Myc-induced lymphoma

    Author : Linus Plym Forshell; Jonas Nilsson; Lars-Gunnar Larsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Myc; Decitabine; Pim kinase; RCAS-tva; Neurobiology; Neurobiologi; molekylärbiologi; Molecular Biology;

    Abstract : The Myc transcription factor activates expression of genes that promote cellular functions such as proliferation and cell growth. The deregulated Myc expression, characteristic for the tumor cell, also activates apoptosis, which selects for additional genetic changes deactivating the induced cell death. READ MORE

  4. 12. Molecular Studies of Diamond-Blackfan Anemia and Congenital Nail Dysplasia

    Author : Anne-Sophie Fröjmark; Niklas Dahl; Catharina Larsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diamond-Blackfan Anemia; RPS19; RPS24; PIM-1; Erythropoiesis; Cell cycle; Apoptosis; Nail dysplasia; FZD6; WNT signaling; Clinical genetics; Klinisk genetik;

    Abstract : The aim of this thesis is to investigate the effect of genetic mutations on the pathophysiology of two human disorders: Diamond-Blackfan Anemia (DBA) and isolated congenital nail dysplasia. The first part of this thesis (Paper I-III) investigates the mechanism associated with DBA. READ MORE

  5. 13. Nanoplasmonic Sensing of Materials for Energy Applications

    Author : Ferry Nugroho; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; localized surface plasmon resonance; sensors; palladium; PIM-1; microporous polymers; nanofabrication; film thickness dependence; indirect nanoplasmonic sensing; glass transition temperature; carbon capture and storage; adsorption; polymer:fullerene blends; organic photovoltaics; alloy nanoparticles; hydrogen sensors; plasmonic sensors;

    Abstract : Sensors are omnipresent in our daily life. They are used in many applications ranging from the touch screen in our smartphones to more critical contexts such as pollution monitoring. READ MORE

  6. 14. Surface Interactions in Powder Injection Moulding

    Author : Elisabeth Johansson; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; surfactants; powder injection moulding PIM ; rheology; steel powder; surface interactions; XPS; SIMS; adsorption; surface composition;

    Abstract : Powder Injection Moulding (PIM) is an attractive technique for producing complex components in large quantities my means of powder technology. The process includes mixing powder with a suitable binder, usually a thermoplastic polymer. Because of the large attractive forces between small particles the powder can be agglomerated in the binder. READ MORE

  7. 15. Early oncogenic events and defective apoptosis in prostate cancer

    Author : Xiaolei Fang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Prostate cancer; HGPIN; ezrin; pim-1; XAF1; apoptosis; DNA methylation; immunohistochemistry; FISH;

    Abstract : Prostate cancer is one of the most common malignancies in males in the Western world. Although the mechanisms are unclear, it is generally believed that the accumulation of genetic alterations leads to the tumor formation. READ MORE