Search for dissertations about: "PMN"

Showing result 6 - 10 of 43 swedish dissertations containing the word PMN.

  2. 6. Liver transplantation in man. Gastrointestinal perfusion and inflammatory response

    Author : Ebbe Rønholm; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carbondioxide; complement activation; cytokines; endotoxaemia; hydrogen-ion concentration; liver transplantation; laser-Doppler flowmetry; PMN elastase; regional blood flow; reperfusion;

    Abstract : Patients undergoing liver transplantation develop a systemic inflammatory response which eventually continues with development of a multiple organ dysfunction syndrome (MODS). Gastro-intestinal hypoxia or bacterial translocation has been proposed as the "motor" of MODS. READ MORE

  4. 7. Mechanisms for leukocyte-mediated adjustment of endothelial barrier function

    Author : Narinder Gautam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Inflammation; leukocyte extravasation; endothelial cells; vascular permeability; plasma leakage integrin signaling; heparin binding protein; contact phase; bradykinin.;

    Abstract : Extravasation of polymorphonuclear leukocytes (PMN) and associated plasma exsudation are key events in the inflammatory process. The mechanism by which activated PMN may induce increased vascular permeability for macromolecules is not fully understood but crucially dependent on an intact leukocytic beta2 integrin (CD11/CD18) adhesion receptor function. READ MORE

  5. 8. Neutrophil granule proteins : modulators of the immune response

    Author : Oliver Söhnlein; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Polymorphonuclear leukocytes (PMN) are multifunctional cells of the innate immune system which represent the advance guard in inflammatory reactions. Via the release of granule proteins the PMN communicates with the endothelium, monocytes, dendritic cells, and lymphocytes and is thereby critically involved in the fine tuning of the host defense system. READ MORE

  6. 9. Endothelial cell interactions with neutrophils : studies of adhesion and effects of lipoxygenase metabolites and antirheumatic drugs

    Author : Mikael Heimbürger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : adhesion; auranofin; endothelium; gold sodium thiomalate; leukotrienes; lipoxins; neutrophils; PPAR; prednisolone;

    Abstract : Inflammation is a process of vital importance in the defence and elimination of microorganisms as well as in the repair of the damaged tissue. However, inadequate or excessive inflammation leads to inflammatory diseases such as rheumatoid arthritis. READ MORE

  7. 10. Motility of human polymorphonuclear leukocytes : An image processing approach

    Author : Mikael Gustafsson; Erik Gylfe; Linköpings universitet; []
    Keywords : Human polymorphonuclear leukocytes; locomotion; phagocytosis; Saccharomyces cerevisiae; membrane transport; intracellular free calcium; cellular pH; water influx; actin dynamics; digital video microscopy; image processing; fura-2; BCECF; DII; MEDICINE; MEDICIN;

    Abstract : Cell motility is essential for polymorphonuclear leukocyte (PMN) function in the defense against invading microorganisms and in inflammatory processes. Using digital video microscopy and image processing, individual cells were studied during random locomotion, chemotactic locomotion and phagocytosis. READ MORE