Search for dissertations about: "PNPLA"

Found 2 swedish dissertations containing the word PNPLA.

  2. 1. Adipose tissue gene expression & candidate genes for obesity

    Author : Lovisa Johansson; Diabetes - klinisk obesitasforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Insulin resistance; Obesity; Adipose tissue; Adiponutrin; PNPLA; PPARGC1A; Gene expression; Case-control association study; Microarray; Genotyping; Population-based study;

    Abstract : Obesity results from an interaction between genetic and environmental factors and is a growing health problem associated with development of insulin resistance, type 2 diabetes and cardiovascular disease. This thesis has focused on investigating the genetic contribution in obesity and insulin resistance by both candidate and global gene approaches with focus on the adipose tissue. READ MORE

  4. 2. Genetic and metabolic studies of APOE, PCSK9, TM6SF2 and PNPLA3

    Author : Hovsep Mahdessian; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Lipids – including fatty acids (FAs), triglycerides (TGs), cholesterol and cholesterol esters (CEs) – are hydrophobic molecules involved in several important structural and mechanistic processes. Lipids are found in cellular membranes, give posture and stability to the cell, are actively participating in cellular signaling, and act as mediators in several important biological pathways. READ MORE