Search for dissertations about: "POLgamma"

Found 2 swedish dissertations containing the word POLgamma.

  2. 1. Molecular mechanisms of mitochondrial DNA replication

    Author : Teresa Holmlund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Mitochondria; mtDNA; replication; helicase; TWINKLE; POLgamma; POLgammaB; mtSSB; adPEO;

    Abstract : Mitochondria are the energy producing organelles of eukaryotic cells. The organelle has its own genome, the mitochondrial DNA (mtDNA) that encodes 13 subunits of the respiratory chain (RC) complexes, two rRNAs and 22 tRNAs. READ MORE

  4. 2. Molecular mechanisms of mammalian mitochondrial DNA replication and transcription

    Author : Mina Pellegrini; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Mitochondrion; DNA polymerase gamma; mtSSB; TWINKLE; DNA replication; transcription; mTERF; MTERF3; MTERF2; nucleoid;

    Abstract : Mitochondria are cytoplasmic organelles in eukaryotic cells, mainly devoted to the synthesis of ATP, through the Oxydative Phospshorylation System (OXPHOS). The organelle has its own genome, the mitochondrial DNA (mtDNA) that encodes for all the RNA components of the mitochondrial translation apparatus (two rRNAs and 22 tRNAs) and for 13 subunits of the OXPHOS complexes. READ MORE