Search for dissertations about: "POMC"

Showing result 1 - 5 of 16 swedish dissertations containing the word POMC.

  2. 1. Defence on Demand : A physiological perspective on phenotypic plasticity in anti-predator traits

    Author : Jerker Vinterstare; Enhet akvatisk ekologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Phenotypic plasticity; inducible defences; stress physiology; cortisol; immune function; trade-offs; sexual dimorphism; crucian carp; visual ecology; predator-prey interactions; POMC pro-opiomelanocortin ; colour change; eco-immunology; Anti-predator defences; Inducible morphological defence; Phenotypic plasticity; Stress physiology; Cortisol; Immune function; Crucian carp; Predator-prey interactions; Trade-offs; Sexual dimorphism; POMC; Pro-opiomelanocortin; Visual ecology; Eye evolution; Melanin; Eco-immunology; Pace-of-life; Behavioural plasticity;

    Abstract : Almost all species face some degree of predation risk, and, hence, evolution has produced a plethora of anti-predator defences. However, anti-predator strategies require resources, and the prevailing risk of becoming prey is influenced by many factors and rarely constant across time and space. READ MORE

  4. 2. Neuroendocrinology of agonostic interaction and social signalling in Artic charr (Salvelinus alpinus) : Studies on the neuroendocrine regulation of aggressive behaviour, stress responses and skin colour

    Author : Erik Höglund; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Brain monoamines; social signalling; POMC; skin colour; stress; Salmonid; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; limnologi; Limnology;

    Abstract : This thesis shows that socially subordinate Arctic charr (Salvelinus alpinus) display elevated brain serotonergic (5-HT) and norepinephric activity along with a chronic activation of the hypothalamic-pituitary-interrenal (HPI) axis, including elevated plasma concentrations of á-MSH. Furthermore, subordinate fish showed an inhibition of aggressive behaviour and darker body coloration, skin darkness being positively correlated with plasma á-MSH. READ MORE

  5. 3. Hypothalamic neuronal circuits involved in the regulation of food intake and body weight : histochemical studies in lean rats and obese mutant mice

    Author : Matilda Bäckberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : AGRP; arcuate nucleus; BBB; CART; GABA; GABA receptors; immunohistochemistry; in situ hybridization; hypothalamus; LHA; leptin; MCH; NPY; orexin; POMC; tubby;

    Abstract : Obesity is a major health problem because of its dramatic increase in prevalence and its association with type 2 diabetes, coronary heart diseases, hypertension and stroke. It is well known that signals generated in response to feeding behavior are integrated in the brain. READ MORE

  6. 4. Brain control of energy balance : localization and regulation of proteins involved in the central control of food intake and body weight

    Author : Maria Collin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : AGRP; arcuate nucleus; brainstem; CART; GABA; Glutamate; GPCR; habenular complex; immunohistochemistry; in situ hybridization; hypothalamus; leptin; leptin receptor; LHA; MCH; NPY; Ob-Rb; POMC; serotonin; STAT3; transporter; ventromedial hypothalamic nucleus; VGLUT1-3.;

    Abstract : Obesity has become a worldwide threat to human well-being and is now so common that it is beginning to replace undernutrition and infectious disease as the most significant contributor to ill health. Obesity increases the risk for aquiring serious diseases such as diabetes type 2, hypertension, coronary heart disease and certain forms of cancer. READ MORE

  7. 5. Leptin targets in the brain regulating body weight : receptors and down-stream mediators of leptin in neurons of the hypothalamus and brainstem

    Author : Marie-Louise Håkansson Ovesjö; Karolinska Institutet; Karolinska Institutet; []
    Keywords : AGRP; antibody; arcuate nucleus; blood-brain-barrier; body weight; brainstem; CART; CRH; DMX; food intake; GABA; GAD; galanin; hypothalamus; immunohistochemistry; in situ hybridization; lateral hypothalamic area; leptin; leptin receptor; MCH; NPY; obesity; Ob-R; Ob-Rb; oxytocin; paraventricular nucleus; POMC; somatostatin; serotonin; STAT3; supraoptic nucleus; transcription factor; vasopressin; VGAT;

    Abstract : Obesity is a disease which has become a global epidemic that is beginning to replace undernutrition and infectious diseases as the most significant contributor to ill health in the world. In particular, obesity is associated with diabetes mellitus, hypertension and coronary heart disease. READ MORE