Search for dissertations about: "PP2A"

Showing result 11 - 15 of 21 swedish dissertations containing the word PP2A.

  2. 11. Functional Characterization of the Cellular Protein p32 : A Protein Regulating Adenovirus Transcription and Splicing Through Targeting of Phosphorylation

    Author : Christina Öhrmalm; Göran Akusjärvi; Neus Visa; Uppsala universitet; []
    Keywords : Cell and molecular biology; Adenovirus; p32; ASF SF2; E4-ORF4; Splicing; Transcription; CTD; RNA Pol II; Cell- och molekylärbiologi;

    Abstract : Cellular processes involved in the conversion of the genetic information from DNA into a protein are often regulated by reversible phosphorylation reactions. By modulating the phosphorylated status of key proteins their activity can either be enhanced or repressed. READ MORE

  4. 12. Salt-inducible kinase 1 : a novel regulator within a cell sodium-sensing network

    Author : Karin Stenström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Na ; K -ATPase; -adducin; Milan hypertensive and normotensive strain of rats; hypertension; angiotensin II; cardiac hypertrophy; myocyte enhancer factor-2 and nuclear factor of activated T-cells;

    Abstract : Na+, K+-ATPase (NK) is expressed in all animal cells and plays a crucial role in cellular ion homeostasis. The NK activity is tightly regulated by specific signaling networks that must be well controlled in time and space (at the plasma membrane or in the intracellular compartments) to guarantee the specificity of the physiological response. READ MORE

  5. 13. Structural studies of three cell signaling proteins : crystal structures of EphB1, PTPA, and YegS

    Author : Amin Bakali; Pär Nordlund; Wenqing Xu; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein production; structural genomics; cell signaling; Biochemistry; Biokemi;

    Abstract : Kinases and phosphatases are key regulatory proteins in the cell. The disruption of their activities leads ultimately to the abolishment of the homeostasis of the cell, and is frequently correlated with cancer. EphB1 is a member of the largest family of receptor tyrosine kinases. It is associated with neurogenesis, angiogenesis, and cancer. READ MORE

  6. 14. The inflammatory response to arterial injury

    Author : Paul Dimayuga; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; neointima; arterial injury; inflammation; Kardiovaskulära systemet;

    Abstract : Atherosclerosis as a disease is postulated to stem from a response to injury of the arterial wall by various stimuli. The inflammatory response is proposed to mediate intimal formation after injury. One pathway of cellular response to injury is through transcription factor NF-kB. READ MORE

  7. 15. Insulin Signalling and Regulation of Protein Kinase B in Adipocytes

    Author : Olga Göransson; Proteinfosforylering; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; secreting systems; Endocrinology; PDK1; PKB; diabetes; insulin; adipocyte;

    Abstract : Insulin resistance is a hallmark of type 2 diabetes, an increasingly common disorder. The cause of insulin resistance is supposedly failures in the processes used by insulin to signal to the interior of its target cells. These failing steps are still unknown, most probably because of incomplete knowledge of how the insulin signals are transmitted. READ MORE