Search for dissertations about: "PP2A"

Showing result 21 - 21 of 21 swedish dissertations containing the word PP2A.

2. 21. The role of mTor in the pathogenesis of tau-related pathologies in Alzheimer disease

   Author : Zhi Tang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : An important neurophathological hallmark of Alzheimer disease (AD) is the progressive formation of neurofibrillary tangles composed of aberrant hyperphosphorylated tau aggregates. Evidence from human postmortem AD brains and in vitro and in vivo rapamycin-treated drug models implicated an abnormal accumulation of the mammalian target of rapamycin (mTor) in AD brains. READ MORE