Search for dissertations about: "PPT"

Showing result 1 - 5 of 31 swedish dissertations containing the word PPT.

  1. 1. TARP Promoter-Based Prostate Cancer Gene Therapy : From Development to Application

    Author : Wing-Shing Cheng; Magnus Essand; Thomas H. Tötterman; Cecilia Lundberg; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Genetic engineering; TARP; PPT; TSTA; promoter; gene regulation; prostate specificity; hormone- independent; adenovirus; prostate cancer; gene therapy; conditionally replicating adenovirus; Genteknik; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Abstract : Prostate cancer is one leading cause of cancer-related death among men in Western countries. The standard therapies for localized prostate cancer include radical prostatectomy and radiation therapy. Such measures are relatively effective in the short term, but many patients ultimately relapse. READ MORE

  2. 2. Adenovirus-mediated CD40 Ligand Immunotherapy of Prostate and Bladder Cancer

    Author : Helena Dzojic; Magnus Essand; Thomas H Tötterman; Aristides Eliopoulos; Uppsala universitet; []
    Keywords : Medicine; immunotherapy; gene therapy; prostate cancer; bladder cancer; adenoviral vector; CD40 ligand; promoter; PPT; TSTA; depsipeptide FK228; TRAMP-C2; Medicin;

    Abstract : Cancer immunotherapy aims at reversing the immunosuppressive tumor environment and enhancing anti-tumor immunity. This thesis comprises studies on murine models for prostate (TRAMP-C2) and bladder (MB49) cancer with the aim to explore if the introduction of an adenoviral vector expressing CD40 ligand (AdCD40L) can induce anti-tumor immune responses. READ MORE

  3. 3. Analysis of melanins

    Author : Gerd Odh Olsson; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PPT-II; PPT-I; DDT; MIF; tyrosinase related protein. dopachrome tautomerase; 3-dicarboxylic acid; pyrrole-2; 5-tricarboxylic acid; 3; thiazole-4; 5-dicarboxylic acid; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : Mammalian melanins are of two major types, eumelanins and peheomelanins, which often occur together, then called mixed-type melanins. A method has been developed for analysing the various forms of melanins. READ MORE

  4. 4. Estrogen receptors and inflammation in colorectal cancer. Role in prognosis and therapeutic opportunities

    Author : Geriolda Topi; Malmö Cellpatologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal Cancer; Estrogen Receptor alpha; Estrogen receptor beta; Prognosis and survival; Zebrafish; Metastasis; ERB-041; PPT; AZD9496; Mast cells; Cysteinyl leukotriene receptors;

    Abstract : .... READ MORE

  5. 5. Analysis of ginesenosides

    Author : Jian-fang Cui; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : New analytical methods were developed in order to evaluate commercial ginseng preparations and to allow studies on urinary excretion of ginsenosides in humans after consumption of ginseng preparations. An optimized alkaline procedure was developed for cleavage of the glycosidic bonds that was clearly superior to previously reported hydrolysis procedures of ginsenosides because of (a) completeness of the reaction and (b) absence of the artifacts found in acid hydrolysis. READ MORE