Search for dissertations about: "PRI"

Showing result 1 - 5 of 15 swedish dissertations containing the word PRI.

  2. 1. Pituitary adenylate cyclase activating polypeptide : Expression and neurotrophic activity in the rat brain

    Author : Ylva Skoglösa; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; in situ hybridisation; rat; TBI; BDNF; NGF; GDNF; PACAP; PRI; TUNEL; apoptosis; CNS; PNS; neuropeptides; neurotrophic factors; reactive oxygen species; Neurovetenskap; Neurology; Neurologi; Neurology; neurologi;

    Abstract : Neurotrophic factors play an important role in regulating naturally occurring cell death during neurogenesis. In addition to classical neurotrophic factors, some neurotransmitters and neuropeptides have been shown to exhibit neurotrophic activities. READ MORE

  4. 2. Life cycle assessment and life cycle cost analysis of a single-family house

    Author : Bojana Petrovic; Ola Eriksson; Marita Wallhagen; Xingxing Zhang; Åsa Wahlström; Högskolan i Gävle; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Building; carbon-dioxide equivalent emissions; global warming potential; primary energy use; life cycle assessment; life cycle cost; Byggnad; koldioxidekvivalenta utsläpp; global uppvärmningspotential; pri-märenergianvändning; livscykelbedömning; livscykelkostnad; Hållbar stadsutveckling; Sustainable Urban Development;

    Abstract : The building industry is responsible for 35% of final energy use and 38% of CO2 emissions at a global level. The European Union aims to reduce CO2 emissions in the building industry by up to 90% by the year 2050. Therefore, it is important to consider the environmental impacts buildings have. READ MORE

  5. 3. Diversifying the transcriptome : Adenosine-to-inosine RNA editing in the mammalian brain

    Author : Albin Widmark; Neus Visa; Joshua Rosenthal; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNA editing; ADAR; microRNA; brain development; neuron; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Metazoan transcriptomes are extensively modified by adenosine-to-inosine (A-to-I) RNA editing, a process by which adenosines within double-stranded RNA are enzymatically deaminated to form inosines. Inosines has base-pairing characteristics similar to guanosine, meaning that A-to-I RNA editing results in functional rewriting of transcripts, affecting many biological processes. READ MORE

  6. 4. Regulation of RNA Editing : The impact of inosine on the neuronal transcriptome

    Author : Mikaela Behm; Marie Öhman; André Gerber; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA editing; ADAR; miRNA; Neuron; Brain development; Synapse; Molecular Biology; molekylärbiologi;

    Abstract : The transcriptome of the mammalian brain is extensively modified by adenosine to inosine (A-to-I) nucleotide conversion by two adenosine deaminases (ADAR1 and ADAR2). As adenosine and inosine have different base pairing properties, A-to-I RNA editing shapes the functional output of both coding and non-coding RNAs (ncRNAs) in the brain. READ MORE

  7. 5. A small amoeba at the crossroads of the big RNAi world : MicroRNA biogenesis and Argonaute function in Dictyostelium discoideum

    Author : Zhen Liao; Fredrik Söderbom; Gerhart E. H. Wagner; Christina Dixelius; Kriton Kalantidis; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNAi; microRNA; Argonaute protein; miRNA biogenesis; Dictyostelium discoideum; social amoeba; Dicer; development; growth; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : Small non-coding RNA (ncRNA) mediated gene silencing, known as RNAi, is a key regulatory mechanism of gene expression in eukaryotes. MicroRNAs (miRNA), one major type of small ncRNAs, are about 21nt long and bound by Argonaute proteins. READ MORE