Search for dissertations about: "PROX1"

Showing result 1 - 5 of 9 swedish dissertations containing the word PROX1.

  2. 1. Towards Novel Biomarkers for Low-grade Glioma

    Author : Shala Ghaderi Berntsson; Anja Smits; Peter Siesjö; Uppsala universitet; []
    Keywords : Low-grade glioma; prognosis; epilepsy; PROX1; DNA repair enzyme; PET; Physiological MRI; Neuroscience; Neurovetenskap;

    Abstract : Gliomas are common primary brain tumours that occur as low-grade (LGG) and high-grade gliomas (HGG). Typically occurring in younger adults, LGG has an indolent course with a median survival of 5-10 years, but carries an inherent potential for transforming into HGG. READ MORE

  4. 2. Towards new tools for clinical evaluation and visualization of tumor growth in patients with glioma

    Author : Kenney Roy Roodakker; Anja Smits; Anne-Marie Landtblom; Elna-Marie Larsson; Jan J. Heimans; Uppsala universitet; []
    Keywords : PROX1; Histology; MRI; PET; Epilepsy; Co-registration; Neurology; Neurologi;

    Abstract : Gliomas are derived from glial cells and are the most common type of primary brain tumors in adults. Gliomas are classified by the World Health Organization (WHO) according to their malignancy grade and histological and molecular features. Malignancy grades range from I to IV. WHO grade I tumors are benign tumors, mostly occurring in childhood. READ MORE

  5. 3. Neuronal Development in the Embryonic Retina : Focus on the Characterization, Generation and Development of Horizontal Cell Subtypes

    Author : Per-Henrik Edqvist; Finn Hallböök; Steven McLoon; Uppsala universitet; []
    Keywords : Neurosciences; Activin; Chick; Follistatin; Interneuron; Isl1; Lim1; Migration; Neurogenesis; Prox1; Transcription factor; Neurovetenskap;

    Abstract : Horizontal cells are retinal interneurons that modulate the output from photoreceptors. Two horizontal cell (HC) subtypes are commonly identified in the vertebrate retina: axon-bearing and axon-less HCs. READ MORE

  6. 4. Transcription factors PROX1 and p53 in cancer development

    Author : Tamador Elsir; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The majority of malignant brain tumors in adults are astrocytic gliomas. These are classified into four malignancy grades according to the World Health Organization (WHO) criteria, including grade I pilocytic astrocytoma, grade II astrocytoma, grade III anaplastic astrocytoma and grade IV glioblastoma. READ MORE

  7. 5. Intratumoral heterogeneity in glioblastoma: subtype transition and cell-to-cell communication

    Author : Min Guo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : glioblastoma; intratumoral heterogeneity; subtype transition; intercellular communication; U-343; SOX2; SFRP2; PROX1; THRAP3; TGFBI; NOTCH1; and ADAMTS1;

    Abstract : Glioblastoma is a most aggressive brain tumor with a median overall survival of less than two years. The current treatment is surgery, chemotherapy, and radiotherapy. However, glioblastoma is difficult to treat and recurs some time after treatment. READ MORE