Search for dissertations about: "PTEN MMAC1"

Found 3 swedish dissertations containing the words PTEN MMAC1.

2. 1. Molecular studies in breast cancer susceptibility genes

   Author : Jindong Chen; Karolinska Institutet; Karolinska Institutet; []
   Keywords : familial breast cancer; breast cancer susceptibility gene; BRCA1; BRCA2; ATM; TP53; PTEN MMAC1; STK11 LKB1; gene mutation; mutation screening; LOH;

   Abstract : Breast cancer is the most common malignancy among women, with a cumulative risk of approximately 12% by the age of 85. Of the breast cancer cases, 5-10% are hereditary. READ MORE

4. 2. Molecular genetic aspects of renal cell carcinoma development

   Author : Andrei Alimov; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Kidney tumor; RCC; LOH; CGH; SKY; PTEN; chromosome 3p; chromosome 10q; chromosome 14q;

   Abstract : Renal cell carcinoma (RCC) is the most common tumor of the renal parenchyma. The aim of this study was to further characterize known as well as new genetic abnormalities in a clinical material of RCC, as well as in established cell lines to gain more information about etiological and progression factors. READ MORE

5. 3. Tracking functional changes in the cancer genome : a molecular genetic analysis of renal and prostatic carcinomas using PCR based techniques by a candidate chromosome and candidate gene approach

   Author : Chunde Li; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Renal cell carcinoma; Prostatic Carcinoma; Molecular Genetics;

   Abstract : Renal cell carcinoma (RCC) is the most common malignancy occurring in the adult kidney. Prostatic carcinoma is the most common male malignancy in most Western countries. Several environmental factors have been suggested to contributed to the tumor genesis but the involvement of genetic factors is also recognized. READ MORE