Search for dissertations about: "PVN"

Showing result 1 - 5 of 7 swedish dissertations containing the word PVN.

2. 1. Hypothalamic and Metabolic Dysfunction in Genetic Models of Huntington’s Disease

   Author : Rana Soylu Kucharz; Translationell neuroendokrinologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington’s Disease; Huntingtin; Hypothalamus; Metabolism; Obesity; orexin; PVN; BAT; TH; neuroendocrinology;

   Abstract : Huntington’s disease (HD) is caused by a CAG trinucleotide repeat expansion in the huntingtin (HTT) gene. HD is an inherited progressive neurodegenerative disorder manifested by the wide array of motor dysfunctions, as well as non-motor symptoms. READ MORE

4. 2. Nitric oxide in central nervous structures associated with water balance and micturition

   Author : Anders Nylén; Lunds universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacological sciences; spinal projections; True Blue; cystometry; circumventricular organs; paraventricular nucleus; supraoptic nucleus; NADPH diaphorase; immunohistochemistry; oxytocin; 8-arginine-vasopressin; hypothalamus; rat; micturition; nitric oxide; water balance; neuronal nitric oxide synthase; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

   Abstract : The role of nitric oxide (NO) in the central control of water balance and micturition has not yet been established. In the present thesis, where female rats were used, neuronal NO synthase (nNOS) distribution was studied in structures of the central nervous system known to be associated with the above mentioned control. READ MORE

5. 3. Central and Peripheral Neuroendocrine Factors in Cancer-Associated Anorexia and Cachexia

   Author : Jonathan R Burgos; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer anorexia-cachexia syndrome; inflammation; TSH receptor; cocaine- and amphetamine-regulated transcript; nesfatin-1; CRH; hypothalamus; brainstem; MCG101;

   Abstract : Cancer anorexia-cachexia syndrome (CACS) develops in response to tumor-host biochemical interactions. A loss of appetite (anorexia) and increased metabolism results in a progressive wasting of adipose and skeletal muscle tissues (cachexia). READ MORE

6. 4. Structure and expression of the TP and EP1 prostanoid receptor genes

   Author : Björn Båtshake; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; Neurologi; neurofysiologi; Neurology; neuropsychology; neurophysiology;

   Abstract : Prostanoids are ubiquitously distributed lipid signaling molecules derived from arachidonic acid, that exhibit numerous and diverse biological effects in a variety of physiological and pathophysiological conditions. The cell surface receptors for the prostanoids belong to the family of G protein-coupled receptors. READ MORE

7. 5. Modulation of the HPA axis alters the sensitivity of the cochlea to acoustic trauma

   Author : Yeasmin Tahera; Karolinska Institutet; Karolinska Institutet; []
   Keywords : HPA axis; corticosterone; glucocorticoid receptor; NFêB; spiral ganglion neurons; cochlea; acoustic trauma; paraventricular nucleus;

   Abstract : The hypothalamic pituitary adrenal axis (HPA axis) regulates nearly all neuroendocrine responses of the body. An active HPA axis is crucial to maintaining homeostasis. An altered reactivity of the HPA axis can affect several physiological systems including the auditory system. READ MORE