Search for dissertations about: "Pain pathway"
Showing result 1 - 5 of 48 swedish dissertations containing the words Pain pathway.
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1. Stuck in mind : the role of catastrophizing in pain
Abstract : Pain catastrophizing emerges in the literature as one of the most important psychological determinants of both pain itself and the negative outcomes commonly associated with it. However, despite decades of research confirming the impact of catastrophizing, there are still areas that remain unexplored or in which the surface has only been scratched. READ MORE
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2. Interactions with pain-related systems - Towards new electrical treatments for chronic pain
Abstract : Background. Persistent intolerable pain is still an unsolved issue with a huge socioeconomic impact. To develop appropriate treatments, it is crucial to understand the complex mechanisms underlying pain and how they change during sustained pain stimuli or during pathological conditions. READ MORE
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3. Signaling Mechanisms in the Neuronal Networks of Pain and Itch
Abstract : Glutamate is the essential neurotransmitters in pain pathways. The discovery of the vesicular glutamate transporters (VGLUT1-3) has been a fundamental step on the way to describe glutamate-dependent pain pathways. We used the Cre-lox system to construct conditional knockouts with deficient Vglut2 transmission in specific neuronal populations. READ MORE
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4. Interactions between the brain and the immune system in pain and inflammation
Abstract : Reciprocal interactions between the nervous and immune systems have gained a lot of attention in the last two decades, especially after demonstrating that cytokine immunotherapies can induce depression and after describing the inflammatory reflex. A lot of effort has been dedicated to understanding how the signals from the immune system reach the brain and vice versa, and on their role in health and disease. READ MORE
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5. Pain in rheumatoid arthritis : bone and neuroinflammation-associated mechanisms
Abstract : Pain is often the primary reason patients with rheumatoid arthritis (RA) seek medical care. Despite effective disease control with currently available disease modifying antirheumatic drugs (DMARDs), there are still hurdles to overcome as a significant proportion of patients still report continuous pain. READ MORE