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Showing result 1 - 5 of 10 swedish dissertations matching the above criteria.

2. 1. Histamine and chromogranin A-derived peptides in rat stomach ECL cells

   Author : Per Norlén; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacy; pharmacognosy; Pharmacological sciences; CGRP adrenaline; galanin; VIP; PACAP; somatostatin; gastrin; microdialys; pancreastatin; chromogranin A; histamine; ECL cell; rat stomach; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

   Abstract : The ECL cells constitute the predominant endocrine cell population of the stomach. They secrete histamine which is a major stimulator of acid secretion. Chormogranin A (CgA)-derived peptides, such as pancreastatin, are co-secreted with histamine. READ MORE

4. 2. Effect of Cholecystokinin-B/Gastrin Receptor Antagonists on Rat Stomach ECL Cells

   Author : Xi-Qin Ding; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacognosy; Pharmacological sciences; vävnadskultur; histokemi; cytokemi; Histologi; tissue culture; histochemistry; gastrin; cholecystokinin CCK receptors; ECL cells; CCK-B gastrin receptor antagonists; histidine decarboxylase HDC ; histamine; pancreastatin; chromogranin A CGA ; gastric acid secretion.; cytochemistry; Histology; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

   Abstract : The histamine- and pancreastatin- containing ECL cells in the acid-producing mucosa of the rat stomach operate under the control of circulating gastrin. The present work examines how cholecystokinin (CCK)-B/gastrin receptors regulate the activity of the ECL cells. READ MORE

5. 3. Secretory activity in isolated rat stomach ECL cells

   Author : Erik Lindström; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; Calcium channels; Adrenaline; Pancreastatin; Prostaglandin E2; Galanin; Somatostatin; Histamine; Gastrin; VIP; PACAP; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

   Abstract : ECL cells are endocrine/paracrine cells located in the acid-producing part of the stomach. They are important regulators of gastric acid secretion in the stomach by virtue of their histamine synthesizing and secreting capacity. Histamine in turn stimulates parietal cells to secrete acid. READ MORE

6. 4. Physiological and pathophysiological regulation of ECL-cell activity

   Author : Maria Lundgren; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacy; toxicology; Pharmacological sciences; pharmacognosy; Gastroenterologi; endothelin; gastrin; ischemia-reperfusion; Physiology; Fysiologi; Gastro-enterology; pancreastatin; histamine; microdialysis; ECL-cell; stomach; Farmakologi; farmakognosi; farmaci; toxikologi;

   Abstract : The ECL cells are endocrine/paracrine cells located in the acid-producing part of the stomach. They produce and secrete histamine and chromogranin A-derived peptides in response to circulating gastrin. Mobilized histamine stimulates acid secretion from adjascent parietal cells. READ MORE

7. 5. Origin, release and functional significance of the novel gastric hormone ghrelin

   Author : Charlotta Dornonville de la Cour; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicology; Farmakologi; pharmacognosy; pharmacy; Pharmacological sciences; bone metabolism; energy homeostasis; glucagon; insulin; secretion; pancreastatin; somatostatin; histamine; gastrin; gastric acid secretion; ghrelin; gastric motility; A-like cells; farmakognosi; farmaci; toxikologi;

   Abstract : The novel gastric hormone ghrelin was discovered by virtue of its ability to release growth hormone (GH) via interaction with the so-called GH-secretagogue receptor (GHS-R). Earlier only synthetic agents were known to bind with the GHS-R, hence, ghrelin is the first identified endogenous ligand. READ MORE