Search for dissertations about: "Pancreatic"

Showing result 1 - 5 of 621 swedish dissertations containing the word Pancreatic.

2. 1. Pancreatic Endocrine Tumourigenesis : Genes of potential importance

   Author : Térèse A. Johansson; Barbro Eriksson; Britt Skogseid; Gunnar Westin; Martin Bäckdahl; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic endocrine tumour; Multiple endocrine neoplasia type 1; Tumourigenesis; Notch signalling; Notch1; Hes1; Neurog3; Neurod1; Men1; Ascl1; Pou3f4; Pdx1; Rpl10; Dlk1; Dkk1; Tph1; menin; Tumour biology; Tumörbiologi;

   Abstract : Understanding signalling pathways that control pancreatic endocrine tumour (PET) development and proliferation may reveal novel targets for therapeutic intervention. The pathogenesis for sporadic and hereditary PETs, apart from mutations of the MEN1 and VHL tumour suppressor genes, is still elusive. READ MORE

4. 2. Pancreatic Neuroendocrine Tumors : Surgical Treatment and Follow-up

   Author : Josefine Kjaer; Olov Norlén; Kjetil Soreide; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic neuroendocrine tumor; surgery; liver metastases; hepatic resection; liver transplantation; recurrence; Kirurgi; Surgery;

   Abstract : Pancreatic neuroendocrine tumors (Pan-NET), are rare, heterogenous and derive from the hormone producing cells in the pancreas. The functioning tumors that overproduce hormones cause clinical syndromes with specific symptoms due to the hormonal production. READ MORE

5. 3. CCK-dependent pancreatic regulation and pancreatic functional impact on growth in young pigs

   Author : Sofia Rengman; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; pancreatin; pig; exocrine pancreatic insufficiency; pancreatic duct ligation; insulin; entero-pancreatic reflex; CCK-receptors; pentagastrin; Exocrine pancreas; cholecystokinin;

   Abstract : The exocrine pancreas is mainly regulated via neuro-hormonal pathways. CCK-dependent regulatory pathways and CCK-receptor subtype involved seem to differ between mammalian species. READ MORE

6. 4. Effects of Pancreatic Surgery : Quality of Life, Cost-effectiveness and Postoperative Results

   Author : Karin Johansen; Bergthor Björnsson; Per Sandström; Linda Lundgren; Jacob Freedman; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic surgery; Minimally invasive surgical procedures; Octogenarians; Surgical outcome; Quality of life; Cost-effectiveness analysis; Qualitative research;

   Abstract : BACKGROUND  Pancreatic operations are large procedures with high rates of complications and other potentially impactful consequences such as diabetes and pancreatic exocrine insufficiency. Due to this, and due to the fact that the operations are often occasioned by periampullary tumours with a poor prognosis, it is important to evaluate how the operations affect patients in terms of postoperative results and quality of life. READ MORE

7. 5. Advances in the Perioperative Management of Pancreatic Cancer

   Author : Srinivas Sanjeevi; Christoph Ansorge; Sara Regnér; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic cancer; pancreatic ductal adenocarcinoma; prophylactic double bypass; pancreaticojejunostomy; neoadjuvant chemotherapy; post-operative pancreatic fistula; Kirurgi; Surgery;

   Abstract : Surgery is currently the only form of curative treatment for pancreatic cancer, yet five-year survival rates following resection are just 15-20%. Improved hospital care has decreased postoperative mortality to 2% yet morbidity remains high at 50%. Poor survival and high morbidity are driven by several perioperative factors. READ MORE