Search for dissertations about: "Paola Tirassa"

Found 1 swedish dissertation containing the words Paola Tirassa.

2. 1. Peripherally administered choleocystokinin-8 increases neurotrophins in the brain

   Author : Paola Tirassa; Karolinska Institutet; Karolinska Institutet; []
   Keywords : NGF; BDNF; CCK-8; glutamate; GABA; CCK receptors; hypothamalus; hippocampus; Choline Acetyltransferase; fimibria-fornix transection; vagotomy; vagal stimulation; RT-PCR; ELISA;

   Abstract : The aim of this thesis was to test the hypothesis that the gastric hormone Cholecystokinin-8 (CCK-8) can modulate the production of Nerve Growth Factor (NGF) in the brain. NGF is the first discovered and the best characterized neurotrophic factor which plays a crucial role in the survival and development of basal forebrain cholinergic neurons (BFCN). READ MORE