Search for dissertations about: "Paracrine"
Showing result 1 - 5 of 107 swedish dissertations containing the word Paracrine.
-
1. Metabolic and immunological interactions between adipose tissue and breast cancer - implications of obesity in tumor progression
Abstract : Triple-negative breast cancers have fewer treatment options than other breast cancers. The overall goal of this research is to identify new pharmaceutical targets for triple-negative breast cancer through studies of the tumor-promoting crosstalk between tumor and surrounding adipose tissue. READ MORE
-
2. Paracrine regulation of Sertoli cell proliferation
Abstract : The Sertoli cell is a highly differentiated somatic cell in the seminiferous epithelium of the testis. This cell is of prime importance for both testicular development and spermatogenesis. READ MORE
-
3. Hormonal and paracrine influences on Leydig cell steroidogenesis
Abstract : Androgen production by Leydig cells is critical for development of the male reproductive organs and for maintaining normal body homeostasis and fertility later in life. Biosynthesis of testosterone is driven by secretion of the gonadotropin, luteinizing hormone (LH) from the pituitary. READ MORE
-
4. Paracrine and autocrine functions of PDGF in malignant disease
Abstract : Growth factors and their receptors are frequently activated by mutations in human cancer. Platelet-derived growth factor (PDGF)-B and its tyrosine kinase receptor, the PDGF β-receptor, have been implicated in autocrine transformation as well as paracrine stimulation of tumor growth. READ MORE
-
5. Endocrine and paracrine factors related to pregnancy and infertility
Abstract : Unexplained infertility, one of the common gynecological disorders, affecting 10 to 15 % of women worldwide. Recurrent pregnancy loss affects approximately 1 to 3 % of pregnant women with an unknown etiology in 50 % of cases. Endocrine dysfunctions, including thyroid dysfunction, are one of the related factors to female reproductive disturbances. READ MORE