Search for dissertations about: "Parallel Synthesis"

Showing result 1 - 5 of 114 swedish dissertations containing the words Parallel Synthesis.

  2. 1. Iron Carbonyl Mediated Parallel Synthesis

    Author : Henrik Gradén; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; dienyl; scavenger; solid phase; galectin inhibitor; oseltamivir; iron carbonyl complex; polymer bound reagent; cation; linker; parallel synthesis; active ester;

    Abstract : This thesis describes the examination and development of cationic iron carbonyl complexes for use in parallel synthesis both in solution phase and on solid phase. A solution phase methodology for carbon-carbon and carbon-heteroatom formation, utilizing polymer bound reagents and scavengers and amenable for automation has been successfully developed. READ MORE

  4. 2. Methods for Asymmetric Olefination Reactions; Development and Application to Natural Product Synthesis

    Author : Daniel Strand; Tobias Rein; Viresh Rawal; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antitumor agents; Asymmetric Horner-Wadsworth-Emmons; Desymmetrization; Metal-catalyzed olefination; Mucocin; Palladium-catalyzed allylic substitution; Parallel kinetic resolution; Pyranicin; Pyragonicin; Rhenium; Stereoconvergent synthesis; Stereodivergent synthesis; Stereoselective synthesis; Tetrahydropyran; Wittig reaction; Organic chemistry; Organisk kemi;

    Abstract : This thesis deals with the development and application of methods for asymmetric olefinations, in particular Horner-Wadsworth-Emmons (HWE) reactions, in the synthesis of certain natural products. Relying on asymmetric HWE reactions to access key building blocks, two natu-ral products, pyranicin and pyragonicin, were synthesized from common late intermediates. READ MORE

  5. 3. Design and Synthesis of Galectin Inhibitors

    Author : Pernilla Sörme; Barbro Kahl Knutson; U Wellmar; B-G Magnusson; Hakon Leffler; Ulf Nilsson; Yuan C. Lee; Reiko T. Lee; Centrum för analys och syntes; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parallel Synthesis; Inhibitors; Biomedicinska vetenskaper allmänt ; General biomedical sciences; Carbohydrates; Galectins;

    Abstract : Galectins, a lectin family, have shown binding affinities towards b-galactosides. Galectins have been proposed to be involved in a wide range of functions like for example, cell growth, adhesion, migration, chemo taxis and apoptosis. They have also been associated with various cancer types. READ MORE

  6. 4. High-Level Synthesis for SiLago : Advances in Optimization of High-Level Synthesis Tool and Neural Network Algorithms

    Author : Yu Yang; Ahmed Hemani; Zhonghai Lu; Madhura Purnaprajna; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Electronic Design Automation EDA ; Computer Aided Design CAD ; Algorithm-level Synthesis; SiLago; Optimization Techniques; Neural Network; Informations- och kommunikationsteknik; Information and Communication Technology;

    Abstract : Embedded hardware designs and their automation improve energy and engineering efficiency. However, these two goals are often contradictory. The attempts to improve energy efficiency often come at the cost of engineering efficiency and vice-versa. High-level synthesis (HLS) is a good example of this challenge. READ MORE

  7. 5. 3D Magnetic Photonic Crystals : Synthesis and Characterization

    Author : Mei Fang; K.Venkat Rao; Lyubov Belova; Rajeev Ahuja; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; magnetic photonic crystals; photonic band gaps; Fe3O4 nanoparticles; silica; Optical physics; Optisk fysik; Materials science; Teknisk materialvetenskap;

    Abstract : This thesis presents the synthesis methods and the characterizations of magnetic Fe3O4 nanoparticles, silica spheres with Fe3O4 nanoparticles embedded, and three dimensional magnetic photonic crystals (MPCs) prepared from the spheres. The structure, material composition, magnetic and optical properties, photonic band gaps (PBGs), as well as how these properties depend on the concentration of the magnetic nanoparticles, are investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM), vibrating sample magnetometer (VSM), superconducting quantum interference device (SQUID), Faraday rotation (FR) and optical spectrophotometers. READ MORE