Search for dissertations about: "Pascal Dammeyer"

Found 2 swedish dissertations containing the words Pascal Dammeyer.

  2. 1. Cancer vaccine strategies and studies of human thioredoxin reductase splice variants

    Author : Pascal Dammeyer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cancer involves abnormal, uncontrolled proliferation of cells, and evasion from the immune system. Immune evasion can be caused by defects in one or more of the components of the major histocompatibility complex class I antigen machinery, e.g. the beta2-microglobulin (beta2m) molecule. READ MORE

  4. 2. Molecular and cellular strategies to enhance efficacy of T cell-based cancer therapy

    Author : Pascal Dammeyer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : β2-microglobulin; MHC class I antigen defects; immune escape; heal-inducible; amplifier vector; GM-CSF; tumor immunity; T lymphocytes;

    Abstract : A combined approach of vaccination with β2-microglobulin (β2m)-deficient dendritic cells (DCs) and granulocyte-macrophage colony-stimulating factor (GM-CSF) as a potent adjuvant may link cellular and molecular strategies to further enhance anti-tumor T-cell responses. T lymphocytes can mediate a potent anti-tumor immune response. READ MORE