Search for dissertations about: "Pathology of hiv"

Showing result 1 - 5 of 9 swedish dissertations containing the words Pathology of hiv.

  2. 1. Interdisciplinary characterization of T cell dynamics in HIV infection

    Author : Marcus Buggert; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : HIV has caused one of the most devastating pandemics in modern medicine. HIV infects and kills on of the central players in effector immunity, CD4+ T cells, that provide helper mechanisms to all arms of the immune system. READ MORE

  4. 2. Clinical and pathological characteristics of the Uganda genotype of Mycobacterium tuberculosis

    Author : Dan Wamala; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Mycobacterium tuberculosis (Mtb), the aetiological agent of tuberculosis (TB) is the leading infectious cause of death globally. The outcome of Mtb infection is variable and depends on host, bacterial and environmental factors. READ MORE

  5. 3. Strategies for modulation of dendritic cell responses

    Author : Annette E Sköld; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : With increased knowledge in dendritic cell (DC) biology, innate immune receptors and their ligands, and the shaping of adaptive responses, refined approaches to modulate our immune system are today emerging as treatment strategies for chronic infections and severe cancers. At the center of attention stand DCs – the innate immune cells that orchestrate the adaptive immune responses. READ MORE

  6. 4. Dysfunctional phenotype of T cells and their contribution to impaired B cell function during HIV-1 infection

    Author : Rebecka Lantto Graham; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Microbial translocation and increased immune activation have been involved in functional T cell impairments and disease progression during HIV-1 infection. The impact of microbial translocation on the phenotype of memory B cells in HIV-1 infected patients was studied in paper I. READ MORE

  7. 5. Innate immunity in the immunopathogenesis of chronic viral infection

    Author : David Malone; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Natural killer (NK) cells have a key role in control and clearance of viral infections. To carry out this function NK cells are capable of recognising infected cells and responding with induction of apoptosis in these cells, and production of pro-inflammatory cytokines. READ MORE