Search for dissertations about: "Pax6"
Showing result 1 - 5 of 19 swedish dissertations containing the word Pax6.
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1. Genetic analysis of genes found on the 4th chromosome of Drosophila - emphasizing the developmental context of Pax6
Abstract : The small size and the lack of recombination set the fourth chromosome of Drosophila melanogaster apart from the other chromosomes. I have shown that the Minute gene on chromosome 4, earlier named Minute-4, encodes the ribosomal protein RpS3A. Two Pax6 genes, eyeless (ey) and twin of eyeless (toy) are also located on chromosome 4. READ MORE
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2. Human neural stem cells: region-specific properties and prospects for cell therapy
Abstract : Cell replacement by neural transplantation can, in animal models of neurodegenerative diseases, reconstruct damaged brain circuitry. In the clinical situation, the graft material used for cell therapy must, most likely, be of human origin. READ MORE
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3. Aniridia-related keratopathy : structural changes, signaling pathways and clinical aspects
Abstract : Aniridia is a congenital autosomal dominant, bilateral, panocular condition, caused by haploinsufficiency of the Pax6 transcription factor. Aniridia-related keratopathy (ARK) significantly affects vision and quality of life in these patients. READ MORE
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4. Mechanisms controlling striatal projection neurone generation, from patterning to early differentiation
Abstract : The striatum is part of the telencephalon, the most anterior part of the vertebrate brain. From when it first can be identified, telencephalic morphology is highly complex and a wide range of mechanisms has been suggested to participate in its induction, patterning and neurogenesis. READ MORE
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5. On Aniridia in Sweden and Norway
Abstract : Introduction Aniridia (iris more or less missing), is a congenital, dominant, inherited, serious and sight-threatening disease, most often appearing as an isolated eye disorder. It is caused by mutations in the PAX6 gene, the master gene of the development of the eye. Typically, Aniridia causes severe visual impairment. READ MORE