Search for dissertations about: "Pediatrisk Endokrinologi"
Showing result 1 - 5 of 11 swedish dissertations containing the words Pediatrisk Endokrinologi.
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1. Tissue transglutaminase autoantibodies in childhood celiac disease
Abstract : Celiac disease is a prevalent small bowel disease in children caused by permanent intolerance against gliadin, which is the alcohol-soluble fraction of the cereal protein gluten in wheat, rye and barley. Celiac disease is characterized by an inflammatory infiltrate of CD4+ T lymphocytes in the intestinal mucosa leading to damage of villous structure and loss of absorptive surface. READ MORE
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2. Aspects of ZnT8 autoimmunity in childhood type 1 diabetes
Abstract : Type 1 diabetes is one of the most common chronic diseases in childhood and adolescence with an increasing incidence worldwide. It is an autoimmune disease with many autoimmune markers, where the zinc transporter 8 autoantibody (ZnT8A) is the most recent autoantibody discovered. READ MORE
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3. Peripheral neuropathy in type 1 and type 2 diabetes – screening of vibrotactile sense and proteomics in human nerve biopsies
Abstract : .... READ MORE
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4. Autoimmunogenetic Aspects of Vaccine-induced Narcolepsy. As part of the AMINA - Autoimmune Multiple Sclerosis and Narcolepsy Study
Abstract : Narcolepsy type 1 (NT1) is a neurological sleep disorder. The biological cause is the degeneration of hypocretin neurons located in the hypothalamus. It has been suggested that NT1 has an autoimmune pathogenesis, as in most patients, the Human Leukocyte Antigen (HLA)-DQB1*06:02:01 is present. READ MORE
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5. Aspects of chronic autoimmune thyroiditis in children and adolescents
Abstract : The aims of this thesis were to 1) compare different methods for detection of antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb), particulary in children with chronic autoimmune thyroditis (AIT), 2) investigate if maternal enterovirus infection is a risk factor for development of AIT in offspring, 3) ascertain the prevalence of thyroid autoantibodies in cord blood sera from children who later developed AIT, 4) develop a new reference standard for interpretation of normative thyroid volumes in Swedish children, and 5) evaluate the effect of Levothyroxine (L-thyroxine) treatment on thyroid size in children and adolescents with AIT. We found that 1) Methods based on radioimmunoassay (RIA) were more efficient in detecting both TgAb and TPOAb in children with AIT than methods based on agglutination. READ MORE