Search for dissertations about: "Pedigree"

Showing result 1 - 5 of 54 swedish dissertations containing the word Pedigree.

  2. 1. Detecting Deletions by Analysis of Genetic Markers in Pedigrees

    Author : Anna Johansson; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cytogenetics; Genetik; Genetics; Biologi; genetic marker; pedigree; Protein S deficiency; Biology; PROS1; deletion; null allele; cytogenetik;

    Abstract : A deletion is defined as a missing piece of a chromosome, ranging in size from as small as a single base pair to as much as an entire arm of a chromosome. Deletions can cause diseases, but may also have a neutral effect in the genome. READ MORE

  4. 2. Dynamics of inbreeding and genetic rescue in a small population

    Author : Malin Hasselgren; Karin Norén; Carles Vilà; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; inbreeding; inbreeding depression; genetic rescue; fitness; genomics; conservation genetics; mutational load; arctic fox; pedigree; gene flow; zoologisk ekologi; Animal Ecology;

    Abstract : Isolation at small population size can reduce individual fitness and impede population growth caused by inbreeding and genetic drift (i.e. inbreeding depression). Inbreeding depression can however be circumvented by gene flow from unrelated individuals through masking of recessive deleterious alleles and contribute to population persistence (i. READ MORE

  5. 3. Gene Mapping in Ficedula Flycatchers

    Author : Niclas Backström; Hans Ellegren; Juha Merilä; Uppsala universitet; []
    Keywords : collared flycatcher; SNP; linkage disequilibrium; genetic map; pedigree;

    Abstract : In order to get full understanding of how evolution proceeds in natural settings it is necessary to reveal the genetic basis of the phenotypic traits that play a role for individual fitness in different environments. There are a few possible approaches, most of which stem from traditional mapping efforts in domestic animals and other model species. READ MORE

  6. 4. Epidemiological and genetic studies of muliple sclerosis with focus on the Swedish county of Värmland

    Author : Margarita Callander; Anders Svenningsson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inborn genetic diseases; Genetic predisposition to disease; Genetic predisposition to disease; Cluster analysis; Muliple sclerosis; Pedigree; Medical genetics; Medicinsk genetik;

    Abstract : The aim of this study was to perform detailed investigations of a presumed high-risk area, namely the county of Värmland, to see if previous results from our group indicating a high frequency of multiple sclerosis (MS) could be confirmed. We soon identified an aggregation of MS cases in the parish of Lysvik located in the north of Värmland and initiated epidemiological and genetical analyses of the population. READ MORE

  7. 5. International breeding programs to improve health in pedigree dogs

    Author : Shizhi Wang; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : Implementation of breeding programs in order to reduce incidence of inherited disorders and their impact on welfare should be a priority for dog breeders and breeding organizations. In that respect, exchange of breeding animals between countries constitutes a critical point to be taken into account. READ MORE