Search for dissertations about: "Pedro-Otavio Campos-Lima de"

Found 1 swedish dissertation containing the words Pedro-Otavio Campos-Lima de.

2. 1. Control of Epstein-Barr virus infection by cytotoxic T lymphocytes

   Author : Pedro-Otavio de Campos-Lima; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Epstein-Barr virus; Cytotoxic T lymphocytes; T cell receptor; CTLescape mutants;

   Abstract : Cytotoxic T lymphocytes (CTL) play a critical role in response to Epstein-Barr virus (EBV), a widespread human herpes virus that persists in healthy carriers as a latent infection of B cells and is implicated in the pathogenesis of lymphoid and epithelial cell malignancies. Six virus encoded nuclear antigens, EBNA1-6, and three membrane proteins, LMP1, -2A and -2B, are regularly detected in EBV transformed lymphoblastoid cell lines (LCLs). READ MORE