Search for dissertations about: "Pentti Tengvall"
Showing result 6 - 10 of 13 swedish dissertations containing the words Pentti Tengvall.
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6. Bioactive Coatings and Antibacterial Approaches for Titanium Medical Implants
Abstract : The aim of this thesis was to characterize and manufacture coatings and surfaces with antibacterial properties and retained or enhanced bioactivity and biocompatibility. The aim was also to study the optimal composition and parameters of mixtures for debridement of bacterial biofilms on titanium surfaces. READ MORE
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7. Diffusion Controlled Drug Release from Slurry Formed, Porous, Organic and Clay-derived Pellets
Abstract : Coronary artery disease and chronic pain are serious health issues that cause severe discomfort and suffering in society today. Antithrombotic agents and highly potent analgesics play a critical role in improving the recovery process for patients being treated for these diseases. READ MORE
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8. Improved titanium and steel implants : Studies on bisphosphonate, strontium and surface treatments
Abstract : Purpose: The general aim of this thesis was to increase the understanding of biomaterial surface modifications and local delivery of osteoporosis drugs for bone integration. We therefore (i) characterised and investigated model surface coatings for controlled drug delivery in a rat tibia screw model (ii) elucidated the effect of surface treatment for activation of complement system in vitro. READ MORE
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9. Towards surgical use of matrix metalloproteinase biology
Abstract : Matrix metalloproteinases (MMPs), such as collagenases, are a family of enzymes capable of degrading most constituents of the extracellular matrix. MMPs are thought to be involved in the aetiopathogenesis of tendon rupture. Additionally, failure of healing has in some instances been associated with elevated levels of MMPs. READ MORE
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10. Biodegradable gelatin microcarriers in tissue engineering : In vitro studies on cartilage and bone
Abstract : Tissue engineering is a multidisciplinary field that combines cells, biomaterial scaffolds and environmental factors to achieve functional tissue repair. This thesis focuses on the use of macroporous gelatin microcarriers as scaffolds in tissue engineering applications, with a special focus on cartilage and bone formation by human adult cells in vitro. READ MORE