Search for dissertations about: "Peptide bond formation"
Showing result 16 - 20 of 33 swedish dissertations containing the words Peptide bond formation.
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16. Leukotriene A4 hydrolase : exploration of the active sites and catalytic mechanisms by site-directed mutagenesis
Abstract : Leukotriene (LT) A4 is a pivotal intermediate in the biosynthesis of leukotrienes, a family of potent lipid mediators involved in a variety of inflammatory and allergic disorders. The bifunctional zinc metalloenzyme LTA4 hydrolase converts LTA4 into LTB4, one of the most potent chemotaxins known to date. READ MORE
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17. Adaptive Evolution of the Bacterial Translation Machinery
Abstract : The process of protein synthesis via translation is of paramount importance for the existence of life on Earth. The bacterial translation machinery has embraced more than 3.5 billion years of molecular evolution to adapt and function efficiently under the provided physiological conditions. READ MORE
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18. Dynamics in Protein Synthesis, Structural Studies of Translation Factors
Abstract : Protein biosynthesis is performed on ribosomes. The ribosome is a complex of ribosomal RNA and proteins forming two subunits. A messenger RNA strand is decoded on the small subunit by charged aminoacyl transfer RNA (aa-tRNA) molecules and each tRNA molecule delivers its amino acid to the growing polypeptide chain on the large subunit. READ MORE
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19. Exotic Ribosomal Enzymology
Abstract : This thesis clarifies intriguing enzymology of the ribosome, the multiRNA/multiprotein complex that catalyzes protein synthesis (translation). The large ribosomal RNAs (23S and 16S rRNAs in E. coli) are post-transcriptionally modified by many specific modification enzymes, yet the functions of the modifications remain enigmatic. READ MORE
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20. Structure analysis and molecular recognition studies of bio-functionalized surfaces
Abstract : Biological and chemical reactions involved in physiological processes are often complex and very sophisticated. Such processes can be mimicked in the laboratory to obtain important knowledge, valuable for the development of new diagnostic methods, drugs and biosensors. READ MORE