Search for dissertations about: "Per Enblad"

Showing result 16 - 20 of 20 swedish dissertations containing the words Per Enblad.

2. 16. Aspects on Mechanisms, Treatment and Outcome in Severe Traumatic Brain Injury

   Author : Teodor Svedung Wettervik; Anders Lewén; Per Enblad; Elham Rostami; Lars-Owe Koskinen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoregulation; clinical outcome; energy metabolism; multimodality monitoring; neurointensive-care; traumatic brain injury; Neurokirurgi; Neurosurgery;

   Abstract : Traumatic brain injury (TBI) is a leading cause for mortality and morbidity worldwide. The primary injury has great impact on patient outcome and cannot be cured, but attentive neurointensive care (NIC) may reduce detrimental secondary brain injuries and is the focus of this thesis. READ MORE

4. 17. Surgical Outcomes in Sagittal Craniosynostosis

   Author : Jesper Unander-Scharin; Daniel Nowinski; Per Enblad; Marie-Lise van Veelen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : The overarching aim of this thesis was to increase the understanding of patient and treatment related factors behind the variability in morphological outcomes seen in nonsyndromic sagittal craniosynostosis. There is a lack of knowledge regarding patient related predictors for the variability in outcomes, and consensus has yet to be reached regarding best practice with respect to surgical technique for the treatment of sagittal craniosynostosis. READ MORE

5. 18. Neurointensive Care of Children with Severe Traumatic Brain Injury : Studies of barbiturate coma treatment, intracranial compliance, pressure autoregulation and optimal cerebral perfusion pressure

   Author : Fartein Velle; Per Enblad; Shruti Agrawal; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic brain injury; Children; Refractory intracranial hypertension; Barbiturate coma; Intracranial compensatory reserve; autoregulation; cerebral microdialysis.; Neurokirurgi; Neurosurgery;

   Abstract : Traumatic brain injury (TBI) is among the most common causes of death and acquired disability during childhood. Management guidelines for pediatric patients are usually extrapolated from adults. Specific pediatric studies are warranted to improve the TBI management in children. READ MORE

6. 19. On the pathophysiology of idiopathic adult hydrosephalus syndrome : energy metabolism, protein patterns, and intracranial pressure

   Author : Aina Ågren Wilsson; Per Enblad; Umeå universitet; []
   Keywords : hydrocephalus; biochemical markers; microdialysis; cerebrospinal fluid; B waves; brain tissue oxygen tension; Neurology; neurologi;

   Abstract : The symptoms in Idiopathic Adult Hydrocephalus Syndrome (IAHS) – gait disturbance, incontinence, and cognitive deficit – correlate anatomically to neuronal dysfunction in periventricular white matter. The pathophysiology is considered to include a cerebrospinal fluid (CSF) hydrodynamic disturbance, including pressure oscillations (“B waves”), in combination with cerebrovascular disease. READ MORE

7. 20. DNA Damage Response of Normal Epidermis in the Clinical Setting of Fractionated Radiotherapy : Evidence of a preserved low-dose hypersensitivity response

   Author : Fredrik Qvarnström; Ingela Turesson; Gunilla Enblad; Mats Harms-Ringdahl; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA damage response; low-dose hypersensitivity; dose response; normal tissue; epidermis; keratinocyte; fractionated radiotherapy; DNA double strand break; DSB; foci; γH2AX; 53BP1; checkpoint; p21; apoptosis; mitosis; Oncology; Onkologi; Oncology; onkologi;

   Abstract : Investigations of DNA damage response (DDR) mechanisms in normal tissues have implications for both cancer prevention and treatments. The accumulating knowledge about protein function and molecular markers makes it possible to directly trace and interpret cellular DDR in a tissue context. READ MORE